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    Using a truss-inspired model with the uniform strength optimization theory to predict spongy bone geometry in proximal femur

    , Article American Journal of Applied Sciences ; Volume 6, Issue 3 , 2009 , Pages 449-455 ; 15469239 (ISSN) Pishdast, H ; Farahmand, F ; Rouhi, G. R ; Sharif University of Technology
    2009
    Abstract
    This paper presents a new naïve approach for simulating bone remodeling process. It is based on the uniform strength theory of optimization and employs a truss-like model for bone. The truss was subjected to external loads including 5 point loads simulating the hip joint contact forces and 3 muscular forces at the attachment sites of the muscles to the bone and the rest are reactions of ligaments. The strain in the links was calculated and the links with high strains were identified. The initial truss is modified by introducing new links wherever the strain exceeds a prescribed or critical value. The critical value was assumed to be equal to an average of the absolute value of strains in the... 

    A Nail Selection Methodology for Intramedullary Nailing of Femoral Fractures Based on the Bone-nail Contact Conditions

    , M.Sc. Thesis Sharif University of Technology Hassanzadeh Isfahani, Mohammadreza (Author) ; Farahmand, Farzam (Supervisor) ; Behzadipour, Saeed (Supervisor)
    Abstract
    Intramedullary nailing procedure is one of the common methods for fixing the fracture of long bones, in which after reduction of a fractured bone and opening up the bone medullary cavity with a drill and metal wire, the surgeon inserts the rod into the bone with continuous strikes. The rod is then tighten to the bone sing the locking screws on the two ends. The mechanical stability of fracture fixation against shear and rotary movement of the two broken parts is essential for the process of repair and fracture treatment. This stability depends on several factors including the difference curvature of the rod and the bone, the bar diameter, the cross-sectional area of the rod, and the function... 

    2-D Bone Structure Prediction of Proximal Femur and Dominant Joint Load Estimation using Level Set Method and Bone RemodelingTheories

    , M.Sc. Thesis Sharif University of Technology Keivan Bahari, Mahsa (Author) ; Farahmand, Farzam (Supervisor) ; Movahhedy, Mohammad Reza (Supervisor) ; Rouhi, Gholamreza (Co-Advisor)
    Abstract
    Bones adapt their form and structure to make an efficient use of their mass against the applied mechanical loads. So, it is not surprising to assume that the geometry and density distribution of a bone contains information about its loading history. The objective of this work was to develop a framework to simulate the bone remodeling procedure as a topology optimization process and then use this framework to develop a simple technique for estimating the dominant joint loads based on the bone’s density distribution.
    At first, the remodeling equation was derived from the structural optimization task of minimizing the strain energy in each time step, using the level set method. Employment... 

    Kinematic Design of a Parallel Robot in Reduction of Femoral Shaft

    , M.Sc. Thesis Sharif University of Technology Kazemirad, Siavash (Author) ; Zohoor, Hassan (Supervisor) ; Farahmand, Farzam (Supervisor)
    Abstract
    The goal of fracture reduction in orthopedic surgery is to reposition the bone fragments in their anatomical orientation (alignment), and the fracture ends closed to each other (apposition). Reduction of long bone fractures is became an interesting subject in the field of robotic aided surgery in pervious decade. Nowadays reduction of femur is carried out by surgeons and medical staff in surgery. Due to the large holding forces necessary, exact positioning is difficult and time consuming. What is needed is an automated system whereby the fractured ends of the bone may be precisely positioned without the need for multiple docking attempts. The fragments need to be held in place as long as... 

    Damage initiation and growth in a long bone under increasing monotonic loading using the continuum damage mechanics principle

    , Article 5th International Conference on Engineering Computational Technology, ECT 2006, Las Palmas de Gran Canaria, 12 September 2006 through 15 September 2006 ; 2006 ; 1905088094 (ISBN); 9781905088096 (ISBN) Kargarnovin, M. H ; Bagher Ebrahimi, M ; Katoozian, H. R ; Sharif University of Technology
    2006
    Abstract
    In this article by employing the principle of continuum damage mechanics and solving the governing equations using finite element technique, the damage process in a composite media like a human long bone has been studied. To do this, primarily a CT scan of a femur is converted to proper model usable for a F.E. model. After applying load incrementally with monotonic nature, the state of stress or strain in each element and consequently in medium are calculated using finite element software. Based on the principle of continuum damage and the value of stress in each element, the damage rate is calculated and the mechanical properties at that point are updated for the next step of loading. This... 

    Stress Analysis of LCP and DCP in Normal and Osteoporosis Femur

    , M.Sc. Thesis Sharif University of Technology Esmaeilpour, Mohammad Rasoul (Author) ; Firoozbakhsh, Keikhosrow (Supervisor)
    Abstract

    Metallic implants are often used in the open reduction and internal fixation of fractures. Open reduction and internal fixation are commonly used in cases of trauma when the bone cannot be healed using external methods such as casting. The locking compression plate combines the conventional screw holes, which use non-locking screws, with locking screw holes, which use locking head screws. This allows for more versatility in the application of the plate.
    In the present work, the stress (von-mises) and deformation of a locking compression plate fixed across a transverse fracture (2-mm gap) at the midshaft of femur was evaluated by Ansys software. Femur model is divided to two part... 

    Design, Simulation, Prototyping and Analysis of a Lengthening Femoral Implant

    , M.Sc. Thesis Sharif University of Technology Mahdavifar, Mohsen (Author) ; Farahmand, Farzam (Supervisor) ; Durali, Mohammad (Supervisor)
    Abstract
    Motorized intramedullary nails are a viable solution to treat patients with limb-length inequality. These fully implanted devices use external magnetic actuation to extend. This research examines the conceptual design of this type of nails by investigating various ideas and previous designs. The implant mechanism, body and controller are designed in detail. It was then simulated in standard tests to evaluate it. In addition, the implanted nail undergoes a biomechanical analysis and its stiffness is assessed. Finally, the controller design is carried out using dipole magnetic theory and verified by finite element simulations. As a proof of concept, we made a prototype that is twice the size... 

    Do the soft tissues located outside tibiofemoral joint have a role in bearing the compressive loads of the joint? An in-vitro study on sheep stifle joints

    , Article Gazzetta Medica Italiana Archivio per le Scienze Mediche ; Volume 172, Issue 7-8 , 2013 , Pages 595-601 ; 03933660 (ISSN) Hakkak, F ; Rostami, M ; Parnianpour, M ; Jabalameli, M ; Sharif University of Technology
    2013
    Abstract
    Aim. The compressive loads on the tibiofemoral joint are normally assumed to be borne solely via contact and pressing of the cartilage surfaces of tibia and femur. However, recent findings suggest that non-contact load-bearing mechanisms are active in the joint as well. In this context, a non-contact load-bearing mechanism involving soft tissue connections outside the tibiofemoral joint has been hypothesized as well. This paper addresses the validity of this hypothesis and the possible involvement of several soft tissue connections outside the joint. Methods. Sheep stifle (knee) joints were studied in vitro. The specimens were loaded in fixed displacement. Various soft tissues outside the... 

    Robotic assisted reduction of femoral shaft fractures using stewart platform

    , Article Studies in Health Technology and Informatics, 19 January 2009 through 22 January 2009 ; Volume 142 , 2009 , Pages 177-179 ; 09269630 (ISSN) ; 9781586039646 (ISBN) Majidifakhr, K ; Kazemirad, S ; Farahmand, F ; Sharif University of Technology
    Abstract
    A robotic system with 6 DOF mobility was proposed for reduction of femoral shaft fractures based on Stewart platform. A plan for implementing the platform on bone fragments was introduced and a step by step strategy for performing the reduction procedure, based on the system's inverse kinematic solution, was proposed. The efficacy of the system was evaluated in some case studies and it was shown that it can be locked to act as an external fixator  

    An analytical approach to study the intraoperative fractures of femoral shaft during total hip arthroplasty

    , Article Journal of Biomechanical Engineering ; Volume 135, Issue 4 , 2013 ; 01480731 (ISSN) Malekmotiei, L ; Farahmand, F ; Shodja, H. M ; Samadi Dooki, A ; Sharif University of Technology
    2013
    Abstract
    An analytical approach which is popular in micromechanical studies has been extended to the solution for the interference fit problem of the femoral stem in cementless total hip arthroplasty (THA). The multiple inhomogeneity problem of THA in transverse plane, including an elliptical stem, a cortical wall, and a cancellous layer interface, was formulated using the equivalent inclusion method (EIM) to obtain the induced interference elastic fields. Results indicated a maximum interference fit of about 210 μm before bone fracture, predicted based on the Drucker-Prager criterion for a partially reamed section. The cancellous layer had a significant effect on reducing the hoop stresses in the... 

    Prediction of shape and internal structure of the proximal femur using a modified level set method for structural topology optimisation

    , Article Computer Methods in Biomechanics and Biomedical Engineering ; Volume 15, Issue 8 , 2012 , Pages 835-844 ; 10255842 (ISSN) Bahari, M. K ; Farahmand, F ; Rouhi, G ; Movahhedy, M. R ; Sharif University of Technology
    Abstract
    A computational framework was developed to simulate the bone remodelling process as a structural topology optimisation problem. The mathematical formulation of the Level Set technique was extended and then implemented into a coronal plane model of the proximal femur to simulate the remodelling of internal structure and external geometry of bone into the optimal state. Results indicated that the proposed approach could reasonably mimic the major geometrical and material features of the natural bone. Simulation of the internal bone remodelling on the typical gross shape of the proximal femur, resulted in a density distribution pattern with good consistency with that of the natural bone. When... 

    A computer model for evaluating the osteotomy parameters of Chiari pelvic osteotomy

    , Article International Orthopaedics ; Volume 34, Issue 3 , 2010 , Pages 329-333 ; 03412695 (ISSN) Karami, M ; Gouran Savadkoohi, D ; Ghadirpoor, A ; Rahimpoor, S ; Azghani, M ; Farahmand, F ; Sharif University of Technology
    2010
    Abstract
    This study was conducted to evaluate the effect of the various osteotomy parameters on the biomechanical aspects of the hip joint on a computerised model. The data of the radiographs and a three-dimensional (3D) CT scan of six patients with coverage deficient hip joint were used to construct a 3D computer model. Then Chiari type osteotomies were simulated using various heights, angles and fibrocartilage thicknesses. A new angle called the mid acetabular center edge (MACE) angle was defined in a mid coronal CT cut. The optimum displacement for obtaining the maximum coverage averaged 73%. The angle and height of the osteotomy had a significant effect on the MACE angle (P value∈<∈0. 01). Our... 

    Electromyographic analysis of anterior cruciate deficient knees with and without functional bracing during lunge exercise

    , Article Prosthetics and Orthotics International ; Volume 40, Issue 2 , 2016 , Pages 270-276 ; 03093646 (ISSN) Jalali, M ; Farahmand, F ; Rezaeian, T ; Ramsey, D. K ; Mousavi, S. M. E ; Sharif University of Technology
    SAGE Publications Inc  2016
    Abstract
    Background: The use of functional knee braces for returning to sports or during demanding activities following anterior cruciate ligament rupture is common; yet despite being commonly prescribed, its mechanism of action remains unknown. Objectives: To examine the effect of functional knee braces on mean muscle activity when performing lunge exercises. Study design: Pre-/post-test (within-subject research design). Methods: A total of 10 male participants with unilateral isolated anterior cruciate ligament deficiency participated. Electromyographic activities of six muscles around the knee were recorded during lunge exercises, with and without wearing a custom functional knee brace. The lunge... 

    Dynamic simulation of biomechanical behaviour of the pelvis in the lateral impact loads

    , Article Journal of Healthcare Engineering ; Volume 2018 , 2018 ; 20402295 (ISSN) Hatami, M ; Wang, D ; Qu, A ; Xiangsen, Z ; Wang, Q ; Baradaran Kazemian, B ; Sharif University of Technology
    Abstract
    The objective of this study was to develop and validate a novel 3D dynamic model of a pelvic side-impactor system. The biomechanical responses of a pelvic flexible model (having.mnf file suffix) under the lateral impact load for predicting the bone fracture mechanism are investigated as well. The 3D solid model of the side-impactor system was imported into MSC/ADAMS software for analyzing the dynamic model, and the pelvic flexible model was extracted from the CT images of a Chinese female volunteer. The flexible model of the pelvis system was developed considering a wide range of mechanical properties in the bone complex and soft tissue to achieve a realistic biomechanical response during a... 

    Assessment of lumbar spinal disc injury in frontal crashes

    , Article Computers in Biology and Medicine ; Volume 123 , 2020 Amiri, S ; Naserkhaki, S ; Parnianpour, M ; Sharif University of Technology
    Elsevier Ltd  2020
    Abstract
    Frontal vehicle crashes have been a leading cause of spinal injuries in recent years. Reconstruction of frontal crashes using computational models and spinal load analysis helps us understand the patterns of injury and load propagation during frontal crashes. By reconstructing a real crash test and using a viscoelastic crash dummy model, spinal injury patterns were analyzed. The results indicated that a moderate crash with an impact speed of 56 km/h leads to injuries in L1-L2 and L5-S1 levels (L for lumbar and S for sacral vertebrae). The largest spinal loads and injuries were mainly observed immediately after the airbag deployment when the peak of the crash acceleration transpires. Also,... 

    Differences in muscle synergies between healthy subjects and transfemoral amputees during normal transient-state walking speed

    , Article Gait and Posture ; Volume 76 , February , 2020 , Pages 98-103 Mehryar, P ; Shourijeh, M. S ; Rezaeian, T ; Khandan, A. R ; Messenger, N ; O'Connor, R ; Farahmand, F ; Dehghani Sanij, A ; Sharif University of Technology
    Elsevier B. V  2020
    Abstract
    Background: Lower limb amputation is a major public health issue globally, and its prevalence is increasing significantly around the world. Previous studies on lower limb amputees showed analogous complexity implemented by the neurological system which does not depend on the level of amputation. Research question: What are the differences in muscle synergies between healthy subjects (HS) and transfemoral amputees (TFA) during self-selected normal transient-state walking speed? Methods: thirteen male HS and eleven male TFA participated in this study. Surface electromyography (sEMG) data were collected from HS dominant leg and TFA intact limb. Concatenated non-negative matrix factorization... 

    Computer simulation of knee arthrometry to study the effects of partial ACL injury and tibiofemoral contact

    , Article 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08, Vancouver, BC, 20 August 2008 through 25 August 2008 ; 2008 , Pages 895-898 ; 9781424418152 (ISBN) Rahemi, H ; Farahmand, F ; Rezaeian, T ; Parnianpour, M ; Sharif University of Technology
    IEEE Computer Society  2008
    Abstract
    We simulated the knee arthrometry test to obtain a deeper understanding of the joint's stability behavior and interpret the arthrometric results more effectively. A 2D sagittal plane finite element model of the lower limb in the standard configuration of knee arthrometry was developed using ANSYS APDL. A detailed model of the knee joint was considered including the femoral articulating contour represented by an ellipse, the tibial plateau represented by a circular arc, and four major knee ligaments and their individual bundles represented by linear and nonlinear tensile springs. A deformable layer of articular cartilage was also considered over the tibial plateau to simulate the bones... 

    A rigid body spring model to investigate the lateral shift-Restraining force behavior of the patellar

    , Article 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07, Lyon, 23 August 2007 through 26 August 2007 ; 2007 , Pages 4679-4682 ; 05891019 (ISSN) ; 1424407885 (ISBN); 9781424407880 (ISBN) Jafari, A ; Farahmand, F ; Meghdari, A ; Sharif University of Technology
    2007
    Abstract
    Patellar lateral stability was studied using a 2D transverse plane model with deformable articular surfaces. Quadriceps muscles and patellar tendon were considered as strings with predefined forces and lateral and medial retinaculum as tensile springs. Deformation behavior of articular cartilage was modeled by a set of compression springs perpendicular to articular surfaces, based on rigid body spring model method (RBSM). Patellar lateral stability was investigated using restraining force method (the external force required to cause up to 10 mm lateral displacement on patella). The results were in good agreement with experimental reports for normal joint, vastus lateralis and vastus medialis... 

    A patient specific finite element simulation of intramedullary nailing to predict the displacement of the distal locking hole

    , Article Medical Engineering and Physics ; Volume 55 , May , 2018 , Pages 34-42 ; 13504533 (ISSN) Mortazavi, J ; Farahmand, F ; Behzadipour, S ; Yeganeh, A ; Aghighi, M ; Sharif University of Technology
    Elsevier Ltd  2018
    Abstract
    Distal locking is a challenging subtask of intramedullary nailing fracture fixation due to the nail deformation that makes the proximally mounted targeting systems ineffective. A patient specific finite element model was developed, based on the QCT data of a cadaveric femur, to predict the position of the distal hole of the nail postoperatively. The mechanical interactions of femur and nail (of two sizes) during nail insertion was simulated using ABAQUS in two steps of dynamic pushing and static equilibrium, for the intact and distally fractured bone. Experiments were also performed on the same specimen to validate the simulation results. A good agreement was found between the model... 

    The effects of trochlear groove geometry on patellofemoral joint stability - A computer model study

    , Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 222, Issue 1 , 2008 , Pages 75-88 ; 09544119 (ISSN) Jafari, A ; Farahmand, F ; Meghdari, A ; Sharif University of Technology
    2008
    Abstract
    The effect of the variation in the femoral groove geometry on patellofemoral joint stability was studied using a two dimensional transverse plane model with deformable articular surfaces. The femoral and patellar bony structures were modelled as rigid bodies with their profiles expressed by splines. The articular cartilage was discretized into compression springs, distributed along the femoral and patellar profiles, based on the rigid-body spring model. The medial and lateral retinacula were modelled as linear tensile springs, and the quadriceps muscles and patellar tendon as strings with known tension. The anatomical data were obtained from the transverse plane magnetic resonance images of...