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    2D computational fluid dynamic modeling of human ventricle system based on fluid-solid interaction and pulsatile flow

    , Article Basic and Clinical Neuroscience ; Volume 4, Issue 1 , 2013 , Pages 64-75 ; 2008126X (ISSN) Masoumi, N ; Framanzad, F ; Zamanian, B ; Seddighi, A. S ; Moosavi, M. H ; Najarian, S ; Bastani, D ; Sharif University of Technology
    2013
    Abstract
    Many diseases are related to cerebrospinal fluid (CSF) hydrodynamics. Therefore, understanding the hydrodynamics of CSF flow and intracranial pressure is helpful for obtaining deeper knowledge of pathological processes and providing better treatments. Furthermore, engineering a reliable computational method is promising approach for fabricating in vitro models which is essential for inventing generic medicines. A Fluid-Solid Interaction (FSI)model was constructed to simulate CSF flow. An important problem in modeling the CSF flow is the diastolic back flow. In this article, using both rigid and flexible conditions for ventricular system allowed us to evaluate the effect of surrounding brain...