Search for: fluid-structure-interaction--fsi
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    Numerical simulations of haemodynamic factors and hyperelastic Circumferential Strain/Stress in the ideal and healthy-patient-specific carotid bifurcations for different rheological models

    , Article International Journal of Biomedical Engineering and Technology ; Volume 6, Issue 4 , 2011 , Pages 387-412 ; 17526418 (ISSN) Toloui, M ; Nikparto, A ; Firoozabadi, B ; Saidi, M. S ; Sharif University of Technology
    To explore the role of hemodynamic in the initiation and progression of stenosis in carotid artery bifurcation, a Computational Fluid Dynamics (CFD) technique is applied. The effect of four rheology models is investigated as well as various mechanical phenomena. In this study, a Finite Element Method (FEM) was applied to simulate the physiologic Circumferential Strain/Stress (CS) Meanwhile, to investigate the role of vessel wall flexibility, a Fluid-Structure Interaction (FSI) analysis was applied. It was concluded that velocity profiles and WSS show sensitivity to arterial wall stiffening while shear thinning models do not have a dominant effect on the flow field  

    A numerical study of the effects of blood rheology and vessel deformability on the hemodynamics of carotid bifurcation

    , Article Scientia Iranica ; Volume 19, Issue 1 , February , 2012 , Pages 119-125 ; 10263098 (ISSN) Toloui, M ; Firoozabadi, B ; Saidi, M. S ; Sharif University of Technology
    Hemodynamic factors, such as Wall Shear Stress (WSS), play a substantial role in arterial diseases. In the larger arteries, such as the carotid artery, interaction between the vessel wall and blood flow affects the distribution of hemodynamic factors. In the present study, both rigid-wall and deformable-wall models are developed in a 3D numerical simulation to assess the effectiveness of arterial rigidity on worsening hemodynamics, especially WSS. Two different rheological models (Newtonian and CarreauYasuda) have been employed to evaluate the influence of blood, non-Newtonian properties, as well. The importance of vessel wall deformability was compared with the rheological model of blood.... 

    Fsi simulation of a healthy coronary bifurcation for studying the mechanical stimuli of endothelial cells under different physiological conditions

    , Article Journal of Mechanics in Medicine and Biology ; Volume 15, Issue 5 , October , 2015 ; 02195194 (ISSN) Pakravan, H. A ; Saidi, M. S ; Firoozabadi, B ; Sharif University of Technology
    World Scientific Publishing Co. Pte Ltd  2015
    Atherosclerosis is a world-spread and well-known disease. This disease strongly relates to the endothelial cells (ECs) function. Normally, the endothelial cells align in the flow direction in the atheroprotected sites; however, in the case of atheroprone sites these cells orient randomly. The mechanical stimuli such as wall shear stress and strains could determine the morphology and function of the endothelial cells. In the present study, we numerically simulated the left main coronary artery (LCA) and its branches to left anterior descending (LAD) and left circumflex coronary (LCX) artery using fluid-structure interaction (FSI) modeling. The results were presented as longitudinal and... 

    Pulsatile blood flow in total cavopulmonary connection: a comparison between Y-shaped and T-shaped geometry

    , Article Medical and Biological Engineering and Computing ; Volume 55, Issue 2 , 2017 , Pages 213-224 ; 01400118 (ISSN) Rajabzadeh Oghaz, H ; Firoozabadi, B ; Saidi, M. S ; Monjezi, M ; Navabi Shirazi, M. A ; Malakan Rad, E ; Sharif University of Technology
    Springer Verlag  2017
    Single-ventricle anomaly is a hereditary heart disease that is characterized by anatomical malformations. The main consequence of this malformation is desaturated blood flow, which without proper treatment increases the risk of death. The classical treatment is based on a three-stage palliative procedure which should begin from the first few days of patient’s life. The final stage is known as Fontan procedure, in which inferior vena cava is directly connected to pulmonary arteries without going through the ventricle. This connection is called total cavopulmonary connection (TCPC). After surgery, the single ventricle supplies adequate and saturated systemic blood flow to the body; however,...