Sharif Digital Repository

In this work, the human lung alveoli are idealized by a three dimensional honeycomb like geometry and a fluid-structure analysis is performed to study the normal breathing mechanics. In contrast to previous works in which the inlet flow rate is predefined, in this model, we have applied a negative pressure on the outside surface of the alveolus which causes air to flow in and out of the alveolus. The integration of the experimental curve of breathing flow rate was used to approximate the shape of the external applied pressure. Our Fluid-Structure Interaction (FSI) model has an advantage over other literature since it addresses both the fluid dynamics and solid mechanics, simultaneously. The... 

The prediction of deposition efficiency of submicron particles in the pulmonary alveoli has received special attention due to its importance for drug delivery systems and for assessing air pollutants health risks. In this work, the pulmonary alveoli of a healthy human are idealized by a three-dimensional honeycomb-like configuration and a fluid-structure interaction analysis is performed. In contrast to previous works in which the inlet flow rate is predefined, in this model, a negative pressure is imposed on the outside surface of the flalveolus which causes air to flow in and out of the alveolus. The resulting flow patterns confirmed that there was no circulation in the terminal alveolus.... 

In this paper, a fluid-structure interaction model for stability analysis of shells conveying fluid is developed. This model is developed for shells of arbitrary geometry and structure and is based on incompressible potential flow. The boundary element method is applied to model the potential flow. The fluid dynamics model is derived by using an inflow/outflow model along with the impermeability condition at the fluid-shell interface. This model is applied to obtain the flow modes and eigenvalues, which are used for the modal representation of the flow field in the shell. Based on the mode shapes and natural frequencies of the shell obtained from an FEM model, the modal analysis technique is...