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Facile and green one-pot synthesis of fluorophore chromeno[4,3-b]quinolin-6-one derivatives catalyzed by halloysite nanoclay under solvent-free conditions
, Article ChemistrySelect ; Volume 4, Issue 8 , 2019 , Pages 2301-2306 ; 23656549 (ISSN) ; Nasr Esfahani, M ; Baltork, I. M ; Mirkhani, V ; Moghadam, M ; Tangestaninejad, S ; Kia, R ; Sharif University of Technology
Wiley-Blackwell
2019
Abstract
In this study, we demonstrated a straightforward method for the easy access of chromeno[4,3-b]quinolin-6-ones via a one-pot three-component reaction of 4-hydroxycoumarin, aldehydes and aryl amines in the presence of halloysite nanoclay as an eco-friendly, inexpensive and green heterogeneous catalyst under solvent-free conditions. Moreover, symmetric and unsymmetric bis-chromeno[4,3-b]quinolin-6-ones were obtained from dialdehyde or diamines in good yields by this method. To date, this is the first report on the synthesis of symmetric and unsymmetric bis-chromeno[4,3-b]quinolin-6-ones via such a one-pot, multicomponent reaction. Some prepared chromeno[4,3-b]quinolin-6-ones displayed as...