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    Application of a new spherical super element in predicting the deformation of biological cells in microinjection

    , Article Proceedings of the ASME Design Engineering Technical Conference, 28 August 2011 through 31 August 2011 ; Volume 7 , August , 2011 , Pages 41-49 ; 9780791854846 (ISBN) Sarvi, M. N ; Ahmadian, M. T ; Sharif University of Technology
    2011
    Abstract
    Biological cell injection is a sensitive and important work which is implemented in injection of foreign materials into individual cells. Microinjection is significantly developed in the field of drug discovery and genetics so predicting the behavior of cell in microinjection is remarkably important because a tiny excessive manipulation force can destroy the tissue of the biological cell. There are a few analytical methods available to simulate the cell injection, hence the numerical methods such as FEM are suitable to be used to model the microinjection. In this study, a new spherical super element is presented to model the biological cells and deformation of a specific cell under an... 

    Comparison of deformation analysis of a biological cell under an injection force using analytical, experimental and finite element methods and Artificial Neural Network

    , Article ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011 ; Volume 2 , 2011 , Pages 499-507 ; 9780791854884 (ISBN) Sarvi, M. N ; Ahmadian, M. T ; ASME ; Sharif University of Technology
    Abstract
    Biological cell injection is a sensitive and important work which is implemented in injection of foreign materials into individual cells. Microinjection is significantly developed in the field of drug discovery and genetics so predicting the behavior of cell in microinjection is remarkably important because a tiny excessive manipulation force can destroy the tissue of the biological cell. There are a few analytical methods available to simulate the cell injection, hence the numerical methods such as FEM are suitable to be used to model the microinjection. In this study, a new spherical super element is presented to model the biological cells and deformation of a specific cell under an...