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    Synthesis and characterization of bioactive glass/forsterite nanocomposites for bone and dental implants

    , Article Ceramics - Silikaty ; Volume 56, Issue 4 , 2012 , Pages 331-340 ; 08625468 (ISSN) Kamalian, R ; Yazdanpanah, A ; Moztarzadeh, F ; Ravarian, R ; Moztarzadeh, Z ; Tahmasbi, M ; Mozafari, M ; Sharif University of Technology
    2012
    Abstract
    In this research, bioactive glass (BG) of the type CaO-P2O 5-SiO2 and nanocrystalline forsterite (NF) bioceramic were successfully synthesized via sol-gel processing method. Heat-treatment process was done to obtain phase-pure nanopowders. After characterization of each sample, the nanocomposite samples were prepared by cold pressing method and sintered at 1000°C. The samples were fully characterized by X-ray powder diffraction (XRD), scanning electron microscope (SEM), energy dispersive spectroscopy (EDX), Fourier transform infrared spectroscopy (FTIR) analyses. The average nanocrystallite size was determined using the Debye-Scherrer's formula 19.6 nm. The bioactivity was examined in vitro... 

    Thermoplastic starch/ethylene vinyl alcohol/forsterite nanocomposite as a candidate material for bone tissue engineering

    , Article Materials Science and Engineering C ; Volume 69 , 2016 , Pages 301-310 ; 09284931 (ISSN) Mahdieh, Z ; Bagheri, R ; Eslami, M ; Amiri, M ; Shokrgozar, M. A ; Mehrjoo, M ; Sharif University of Technology
    Elsevier Ltd 
    Abstract
    Recently, biodegradable polymers such as starch based blends have been well renowned in the biomedical field. Studies have considered them suitable for bone scaffolds, bone cements, tissue engineering scaffolds, drug delivery systems and hydrogels. The aim of this study was to synthesize nanocomposite biomaterial consisting a blend of thermoplastic starch and ethylene vinyl alcohol as the polymer matrix, and nano-structured forsterite as the ceramic reinforcing phase for bone tissue engineering applications. Furthermore, vitamin E was applied as a thermal stabilizer during melt compounding. Extrusion and injection molding were incorporated for melt blending and shaping of samples,... 

    Design and Fabrication of Polymeric Scaffold by 3D Bioprinter for Skull Bone Tissue Engineering

    , M.Sc. Thesis Sharif University of Technology Saberi, Fatemeh (Author) ; Mashayekhan, Shohreh (Supervisor)
    Abstract
    Cranioplasty is a surgical procedure for repairing skull defects. This surgery will protect the brain tissue, reduce pain in the lesion site and reduce the psychological burden on the patient. Cranioplasty implants should have distinct characteristics, i.e., high strength for protecting the brain, full coverage of skull defects, resistance to infection, non-expansion with heat, and reasonable price. Titanium implants, bone allografts, hydroxyapatite, and methyl methacrylate are commonly used in this surgery. However, these materials have many disadvantages that limit their use. As a result, biodegradable material and 3D printing technology are the next steps for designing scaffolds according...