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Intralesional immunotherapy compared to cryotherapy in the treatment of warts
, Article International Journal of Dermatology ; Volume 56, Issue 4 , 2017 , Pages 474-478 ; 00119059 (ISSN) ; Jabbari Azad, F ; Mahboubi Oskouei, Y ; Jafari, M ; Tehranian, S ; Alizadehsani, R ; Layegh, P ; Sharif University of Technology
Blackwell Publishing Ltd
2017
Abstract
Background: Warts are the most common clinical manifestation of the human papilloma-virus infection in the skin and mucous membranes. In spite of the various therapeutic modalities for nongenital skin warts, there is still no single method to be used as an approved treatment. In this study, we compared the efficacy of immunotherapy and cryotherapy on wart lesions. Methods: Sixty patients with verruca vulgaris and plantar warts were randomly divided into two groups. One group received intralesional injection of candida antigen repeated every 3 weeks until complete improvement of all warts or for a maximum of three sessions. The second group was treated by cryotherapy with liquid nitrogen for...