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Escherichia coli bacteria reduce graphene oxide to bactericidal graphene in a self-limiting manner
, Article Carbon ; Volume 50, Issue 5 , 2012 , Pages 1853-1860 ; 00086223 (ISSN) ; Ghaderi, E ; Sharif University of Technology
2012
Abstract
Interactions of chemically exfoliated graphene oxide (GO) nanosheets and Escherichia coli bacteria living in mixed-acid fermentation with an anaerobic condition were investigated for different exposure times. X-ray photoelectron spectroscopy showed that as the exposure time increased (from 0 to 48 h), the oxygen-containing functional groups of the GO decreased by ∼60%, indicating a relative chemical reduction of the sheets by interaction with the bacteria. Raman spectroscopy and current-voltage measurement confirmed the reduction of the GO exposed to the bacteria. The reduction was believed to be due to the metabolic activity of the surviving bacteria through their glycolysis process. It was...
Formulation and characterization of poly (ethylene glycol)-coated core-shell methionine magnetic nanoparticles as a carrier for naproxen delivery: growth inhibition of cancer cells
, Article Cancers ; Volume 14, Issue 7 , 2022 ; 20726694 (ISSN) ; Yeganeh, A. E ; Yousefi, M ; Far, B. F ; Akbarzadeh, I ; Bokov, D. O ; Raahemifar, K ; Soltani, M ; Sharif University of Technology
MDPI
2022
Abstract
An efficient and selective drug delivery vehicle for cancer cells can remarkably improve therapeutic approaches. In this study, we focused on the synthesis and characterization of magnetic Ni1−x Cox Fe2 O4 nanoparticles (NPs) coated with two layers of methionine and polyethylene glycol to increase the loading capacity and lower toxicity to serve as an efficient drug car-rier. Ni1−x Cox Fe2 O4 @Methionine@PEG NPs were synthesized by a reflux method then charac-terized by FTIR, XRD, FESEM, TEM, and VSM. Naproxen was used as a model drug and its loading and release in the vehicles were evaluated. The results for loading efficiency showed 1 mg of Ni1−x Cox Fe2 O4 @Methionine@PEG NPs could load...
Ag-doped magnetic metal organic framework as a novel nanostructured material for highly efficient antibacterial activity
, Article Environmental Research ; Volume 188 , 2020 ; Abdi, J ; Vossoughi, M ; Alemzadeh, I ; Sharif University of Technology
Academic Press Inc
2020
Abstract
In the last decades, numerous attempts have been made to prevent microbial pollution spreading, using antibacterial agents. Zeolitic imidazolate framework-8 (ZIF-8) belongs to a subgroup of metal organic frameworks (MOFs) merits of attention due to the zinc ion clusters and its effective antibacterial activity. In this work, Ag-doped magnetic microporous γ-Fe2O3@SiO2@ZIF-8-Ag (FSZ-Ag) was successfully synthesized by a facile methodology in room temperature and used as an antibacterial agent against the growth of the Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus bacteria. Several characterization methods were applied to analyze the properties of the materials, and the...