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    Carbon-based nanocomposite decorated with bioactive glass and CoNi2S4 nanoparticles with potential for bone tissue engineering

    , Article OpenNano ; Volume 8 , 2022 ; 23529520 (ISSN) Bagherzadeh, M ; Aldhaher, A ; Ahmadi, S ; Baheiraei, N ; Rabiee, N ; Sharif University of Technology
    Elsevier Inc  2022
    Abstract
    In this work, for the first time, different forms of nanocomposites based on rGO and MWCNT were prepared in conjoining with the bioactive glass (BioGlass). In the carbonic layers, a highly toxic nanoparticle, CoNi2S4, was intercalated, and the role of this nanoparticle in the alkaline phosphatase activity, relative cell viability on different cell lines, and also the effect on the cell walls and cell morphologies were investigated. From another perspective, the ability of the chemotherapy drug loading to the prepared nanocomposites was investigated, and the use of leaf extracts was thought of as a green method to lower the cytotoxicity and regulate the genotoxicity of the generated...