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    Smart chip for visual detection of bacteria using the electrochromic properties of polyaniline

    , Article Analytical Chemistry ; Volume 91, Issue 23 , 2019 , Pages 14960-14966 ; 00032700 (ISSN) Ranjbar, S ; Farahmand Nejad, M. A ; Parolo, C ; Shahrokhian, S ; Merkoci, A ; Sharif University of Technology
    American Chemical Society  2019
    Abstract
    Finding fast and reliable ways to detect pathogenic bacteria is crucial for addressing serious public health issues in clinical, environmental, and food settings. Here, we present a novel assay based on the conversion of an electrochemical signal into a more convenient optical readout for the visual detection of Escherichia coli. Electropolymerizing polyaniline (PANI) on an indium tin oxide screen-printed electrode (ITO SPE), we achieved not only the desired electrochromic behavior but also a convenient way to modify the electrode surface with antibodies (taking advantage of the many amine groups of PANI). Applying a constant potential to the PANI-modified ITO SPE induces a change in their... 

    Controlled drug delivery using the magnetic nanoparticles in non-Newtonian blood vessels

    , Article Alexandria Engineering Journal ; 2020 Abu Hamdeh, N. H ; Bantan, R. A. R ; Aalizadeh, F ; Alimoradi, A ; Sharif University of Technology
    Elsevier B.V  2020
    Abstract
    Fouling in blood flow is very common and may decrease the blood flow in human body and lead to critical health issues. Upon injury in a blood vessel, the body's defensive system triggers a process to create a blood clot called “Thrombus”, which prevents bleeding. Blood clots are formed by a combination of blood cells, platelets, and fibrins. In this study, we investigate a controlled drug delivery using the magnetic nanoparticles in blood vessels under the influence of magnetic fields. For this purpose the Maxwell and the Navier-Stokes equations for the system are solved. In contrary to the previous studies it is assumed that the blood is a non-Newtonian fluid. The number of particles has...