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    Designing Polymeric Biomaterials based on Polysaccharides with Tissue Adhesion and Hemostasis Performance

    , M.Sc. Thesis Sharif University of Technology Shokrani, Hanieh (Author) ; Mashayekhan, Shohreh (Supervisor) ; Kordzadeh, Azadeh (Co-Supervisor)
    Abstract
    Death can be the result of severe bleeding which is associated with the loss of a high amount of blood like what happens in accidents, wars, or operations. Classic methods to stop bleeding are mostly ineffective to decrease the hemostasis time and the volume of the lost blood. A wide variety of products like powders, foams, and hydrogels have been designed and synthesized either from natural or synthetic polymers. However, limitations like weak tissue adhesion, creating a moist environment in the wound site, infection, weak biodegradation, and hemolysis still have remained. Among the existing options to be used as hemostasis agents, polysaccharides can be appropriate considering their great...