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Numerical Simulation of Blood clot Formation and Growth and Investigating the Effect of Blood Rheology on this Process
, M.Sc. Thesis Sharif University of Technology ; Firoozabadi, Bahar (Supervisor)
Abstract
Blood clot formation in the heart vessels begins with damage to the vessel wall. This triggers the deposition of platelets at the site of injury. Finally, to stabilize the clot, a fibrin network forms over the accumulated platelets. In this study, a mathematical model was employed to analyze the growth of blood clots in stenosed vessels. The blood hydrodynamics were modeled by solving the continuity and Navier-Stokes equations, while the transport species involved in biological reactions were captured using the convection-diffusion-reaction equations. The simulations were conducted using Fluent software in two modes: fixed geometry and moving geometry. In the fixed geometry case, platelet...