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    Pemphigus vulgaris and infections: A retrospective study on 155 patients

    , Article Autoimmune Diseases ; Volume 2013 , 2013 ; 20900430 (ISSN) Esmaili, N ; Mortazavi, H ; Noormohammadpour, P ; Boreiri, M ; Soori, T ; Vasheghani Farahani, I ; Mohit, M ; Sharif University of Technology
    2013
    Abstract
    Background. Autoimmune process and immunosuppressive therapy of pemphigus vulgaris would predispose the patients to infections. Aim. We aimed to study the prevalence of infection and pathogenic agents in pemphigus vulgaris patients admitted to dermatology service. Material and methods. This retrospective study was conducted on 155 pemphigus vulgaris patients (68 males, 87 females) admitted to dermatology service between 2009 and 2011. In this study, the diagnosis of pemphigus vulgaris was confirmed by light microscopic and direct immunofluorescence findings. Data were collected through a questionnaire. Results. Of 155 pemphigus vulgaris patients, 33 had infection at admission and 9 acquired... 

    Viral infected cells reveal distinct polarization behavior; a polarimetric microscopy analysis on HSV infected Vero and HeLa cells

    , Article Journal of Quantitative Spectroscopy and Radiative Transfer ; Volume 262 , 2021 ; 00224073 (ISSN) Amiri, S ; Abedini, M ; Badieyan, S ; Vaezjalali, M ; Akhavan, O ; Sasanpour, P ; Sharif University of Technology
    Elsevier Ltd  2021
    Abstract
    The optical polarization properties of virus-infected cells have been measured, analyzed, and compared with the uninfected cells. In this regard, Vero and HeLa cells have been used as the host for Herpes simplex viruses (HSV). By using polarization microscopy imaging technique, the Mueller matrix images of infected and uninfected cells have been recorded. Through image processing and further analysis, the polarization properties of host cells are compared with their infected ones. For quantitative analysis, the multispectral Mueller matrix transformation (MMT) parameters (A and b) are calculated to identify the microstructural differentiations between uninfected and infected cells by HSV....