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heterogeneous-polymers
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First passage time distribution of chaperone driven polymer translocation through a nanopore: Homopolymer and heteropolymer cases
, Article Journal of Chemical Physics ; Volume 135, Issue 24 , 2011 ; 00219606 (ISSN) ; Metzler, R ; Ejtehadi, M. R ; Sharif University of Technology
2011
Abstract
Combining the advection-diffusion equation approach with Monte Carlo simulations we study chaperone driven polymer translocation of a stiff polymer through a nanopore. We demonstrate that the probability density function of first passage times across the pore depends solely on the Péclet number, a dimensionless parameter comparing drift strength and diffusivity. Moreover it is shown that the characteristic exponent in the power-law dependence of the translocation time on the chain length, a function of the chaperone-polymer binding energy, the chaperone concentration, and the chain length, is also effectively determined by the Péclet number. We investigate the effect of the chaperone size on...