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    Effects of hypertension on Intima-Media Thickness (IMT); application to a human carotid artery

    , Article Scientia Iranica ; Volume 23, Issue 4 , 2016 , Pages 1731-1740 ; 10263098 (ISSN) Mirbagheri, S. A ; Saidi, M. S ; Sohrabi, S ; Firoozabadi, B ; Banazadeh, M. H ; Sharif University of Technology
    Sharif University of Technology 
    A vast number of deaths in the world have been attributed to atherosclerosis. The prominent aim of this study is proposing an accurate and simple model to investigate the process of arterial wall thickening. In order to investigate LDL (Low Density Lipoprotein) accumulation in arterial wall, a four layer model for arterial wall consisting of endothelium, intima, IEL, and media is presented. All layers are treated as homogenous porous media. This model has been solved both numerically and analytically. Obtained accumulated LDL in the intima is used to calculate oxidized LDL flux. Also, the presented model and clinical data are used to prepare the growth model for arterial wall. Furthermore,...