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    Fabrication and Optimizing a Bilayer Scaffold with the Ability to Release Growth Factors in Aim to Treating Injuries in Tissue Engineering

    , M.Sc. Thesis Sharif University of Technology Seifi, Saeed (Author) ; Shamloo, Amir (Supervisor) ; Hosseini, Vahid (Supervisor)
    Abstract
    Skin, as the largest organ of the body and the first protector against external injuries, plays an important role in maintaining human health. Therefore, providing a method for complete treatment of skin lesions is very important. In the last century, tissue engineering approaches, with the introduction of skin scaffolds, have been instrumental in the process of skin tissue regeneration and treatment. The aim of the present study is to construct an optimal bilayer scaffold to mimic the two outer layer of the skin (epidermis and dermis). Besides, the effects of placenta extract on acceleration of wound healing was investigated by an in-vivo test. both layer of scaffold are porous hydrogels,...