Sharif Digital Repository

Hydroxyapatite (HA) is the most substantial mineral constituent of a bone which displays splendid biocompatibility and bioactivity properties. Nevertheless, its mechanical property is not utmost appropriate for a bone substitution. Therefore, a composite consist of HA and a biodegradable polymer is usually prepared to generate an apt bone scaffold. In the present work polycaprolactone (PCL) was employed as a matrix and hydroxyapatite nanorods were used as a reinforcement element of the composite. HA/PCL nanocomposites were synthesized by a new in-situ sol-gel process using low cost chemicals. Chemical and physical characteristics of the nanocomposite were studied by X-ray diffraction (XRD),... 

Single-crystal hydroxyapatite (HAp) nanorods and nanogranules have been synthesized successfully by a mechanochemical process using two distinct experimental procedures. The experimental outcomes are characterized by transmission electron microscopy (TEM), and powder X-ray diffraction (XRD) techniques. In this work, the feasibility of using polymeric milling media to prepare hydroxyapatite nanoparticles is described. The resulting hydroxyapatite powder exhibits an average size of about 20 to 23 nm. Final results indicate that the proposed synthesis strategy provides a facile pathway to obtain single-crystal HAp with high quality and suitable morphology. © 2008 Elsevier B.V. All rights...