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A systematic review of nano formulation of natural products for the treatment of inflammatory bowel disease: drug delivery and pharmacological targets
, Article DARU, Journal of Pharmaceutical Sciences ; 2018 ; 15608115 (ISSN) ; Bahramsoltani, R ; Marques, A. M ; Naseri, R ; Rahimi, R ; Haratipour, P ; Panah, A. I ; Farzaei, M. H ; Abdollahi, M ; Sharif University of Technology
Abstract
Inflammatory bowel diseases (IBD), which is classified into Crohn’s disease and ulcerative colitis, are among chronic gastrointestinal diseases with unknown pathogenesis. Diverse strategies have been applied for the treatment of this chronic disease. However, selective and site-specific routes of drug delivery to the inflamed location of the colon remain of high importance. Consequently, the application and effects of natural products in the form of nanoformulation and stimuli responsive nanoparticles as a novel strategy for the treatment of IBD are discussed in this review article. This approach may potentially overcome some complications that are associated with conventional means of colon...
The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the global burden of disease study 2017
, Article The Lancet Gastroenterology and Hepatology ; Volume 5, Issue 1 , 2020 , Pages 17-30 ; Sepanlou, S. G ; Ikuta, K ; Vahedi, H ; Bisignano, C ; Safiri, S ; Sadeghi, A ; Nixon, M. R ; Abdoli, A ; Abolhassani, H ; Alipour, V ; Almadi, M. A. H ; Almasi Hashiani, A ; Anushiravani, A ; Arabloo, J ; Atique, S ; Awasthi, A ; Badawi, A ; Baig, A. A. A ; Bhala, N ; Bijani, A ; Biondi, A ; Borzì, A. M ; Burke, K. E ; Carvalho, F ; Daryani, A ; Dubey, M ; Eftekhari, A ; Fernandes, E ; Fernandes, J. C ; Fischer, F ; Haj Mirzaian, A ; Hasanzadeh, A ; Hashemian, M ; Hay, S. I ; Hoang, C. L ; Househ, M ; Ilesanmi, O. S ; Balalami, N. J ; James, S. L ; Kengne, A. P ; Malekzadeh, M. M ; Merat, S ; Meretoja, T. J ; Mestrovic, T ; Mirrakhimov, E. M ; Mirzaei, H ; Mohammad, K. A ; Mokdad, A. H ; Monasta, L ; Negoi, I ; Nguyen, T. H ; Nguyen, C. T ; Pourshams, A ; Poustchi, H ; Rabiee, M ; Rabiee, N ; Ramezanzadeh, K ; Rawaf, D. L ; Rawaf, S ; Rezaei, N ; Robinson, S. R ; Ronfani, L ; Saxena, S ; Sepehrimanesh, M ; Shaikh, M. A ; Sharafi, Z ; Sharif, M ; Siabani, S ; Sima, A. R ; Singh, J. A ; Soheili, A ; Sotoudehmanesh, R ; Suleria, H. A. R ; Tesfay, B. E ; Tran, B ; Tsoi, D ; Vacante, M ; Wondmieneh, A. B ; Zarghi, A ; Zhang, Z. J ; Dirac, M ; Malekzadeh, R ; Naghavi, M ; GBD 2017 Inflammatory Bowel Disease Collaborators ; Sharif University of Technology
Elsevier Ltd
2020
Abstract
Background: The burden of inflammatory bowel disease (IBD) is rising globally, with substantial variation in levels and trends of disease in different countries and regions. Understanding these geographical differences is crucial for formulating effective strategies for preventing and treating IBD. We report the prevalence, mortality, and overall burden of IBD in 195 countries and territories between 1990 and 2017, based on data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017. Methods: We modelled mortality due to IBD using a standard Cause of Death Ensemble model including data mainly from vital registrations. To estimate the non-fatal burden, we used data...