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    The effects of intra-abdominal pressure on the stability and unloading of the spine

    , Article Journal of Mechanics in Medicine and Biology ; Volume 12, Issue 1 , 2012 ; 02195194 (ISSN) Mokhtarzadeh, H ; Farahmand, F ; Shirazi Adl, A ; Arjmand, N ; Malekipour, F ; Parnianpour, M ; Sharif University of Technology
    Abstract
    In spite of earlier experimental and modeling studies, the relative role of the intra-abdominal pressure (IAP) in spine mechanics has remained controversial. This study employs simple analytical and finite element (FE) models of the spine and its surrounding structures to investigate the contribution of IAP to spinal loading and stability. The analytical model includes the abdominal cavity surrounded by muscles, lumbar spine, rib cage and pelvic ring. The intra-abdominal cavity and its surrounding muscles are represented by a thin deformable cylindrical membrane. Muscle activation levels are simulated by changing the Young's modulus of the membrane in the direction of muscle fibers, yielding... 

    Role of Intra-Abdominal Pressure and Abdominal Muscle Activities on Spinal Stability and Spinal Loads

    , M.Sc. Thesis Sharif University of Technology Farahmand, Masoud (Author) ; ParnianPour, Mohamad (Supervisor) ; Firoozbakhsh, Keikhosrow (Co-Advisor)
    Abstract
    Spine is one of the most important musculoskeletal systems of the human body. Any problem which is related to this part of human body causes pain and disability. Spinal compression forces are one of the main reasons of this disability and pain. It is assumed that intra-abdominal pressure causes spinal unloading in lifting. Studies usually don’t consider the role of intra-abdominal pressure and introduce it as an effective parameter which can increases spinal stability and influences spinal mechanics.Generation mechanism of intra-abdominal pressure remain enigmatic, studies that advocate the unloading effect of IAP usually consider a raise in IAP to be primarily due to the activity of... 

    Investigation of Excitation-contraction behavior in Skeletal Muscle by Means of Chemomechanical Modeling

    , Ph.D. Dissertation Sharif University of Technology Karami, Mina (Author) ; Zohoor, Hassan (Supervisor) ; Firoozbakhsh, Keikhosrow (Supervisor)
    Abstract
    Numerous studies have shown a direct relationship between skeletal muscle active force and intracellular calcium ion concentrations; In fact, no matter how the muscle is stimulated (neurological, electrical, chemical, and mechanical stimuli), the main cause of muscle activation and consequently force generation is calcium ions.According to this scientific finding, the purpose of this study is to present a new chemo-mechanical multiscale model of skeletal muscle based on the fundamental principles of continuum thermodynamics. In this model, unlike other similar studies, muscle active force is not considered as the conventional multiplication of isometric force in a set of corrective... 

    Can lumbosacral orthoses cause trunk muscle weakness? A systematic review of literature

    , Article Spine Journal ; Volume 17, Issue 4 , 2017 , Pages 589-602 ; 15299430 (ISSN) Azadinia, F ; Ebrahimi Takamjani, E ; Kamyab, M ; Parnianpour, M ; Cholewicki, J ; Maroufi, N ; Sharif University of Technology
    Elsevier Inc  2017
    Abstract
    Background Wearing lumbosacral orthosis (LSO) is one of the most common treatments prescribed for conservative management of low back pain. Although the results of randomized controlled trials suggest effectiveness of LSO in reducing pain and disability in these patients, there is a concern that prolonged use of LSO may lead to trunk muscle weakness and atrophy. Purpose The present review aimed to evaluate available evidence in literature to determine whether LSO results in trunk muscle weakness or atrophy. Study Design This is a systematic review. Methods A systematic search of electronic databases including PubMed, Scopus, ScienceDirect, and Medline (via Ovid) followed by hand search of...