Loading...
Search for:
levodopa
0.052 seconds
Detection of L-Dopa Based on Fluorescent of levodopa Nanopolymers and CdTe Quantum Dots
, M.Sc. Thesis Sharif University of Technology ; Hormozi Nezhad, Mohammad Reza (Supervisor)
Abstract
Levodopa [L-3, 4-dihydroxyphenylalanine, or L-DOPA] is an important neurotransmitter used for the treatment of neural disorders such as Parkinson’s disease. Abnormal L-Dopa concentrations in biological fluids can be used for evaluation of diseases such as Parkinson’s diseases. In the first part of this thesis, a rapid and sensitive method for levodopa detection was reported which is based on in situ formation of polylevodopa nanoparticles. The assay is very simple and low cost and uses only NaOH and HCl as reagents. Under alkaline conditions, levodopa is spontaneously oxidized to its quinone derivative and shows the fluorescence properties. The fluorescence signal of the oxidation product of...