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    On the capacity of level and type modulations in Molecular communication with ligand receptors

    , Article IEEE International Symposium on Information Theory - Proceedings, 14 June 2015 through 19 June 2015 ; Volume 2015-June , 2015 , Pages 1951-1955 ; 21578095 (ISSN) ; 9781467377041 (ISBN) Aminian, G ; Mirmohseni, M ; Nasiri Kenari, M ; Fekri, F ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2015
    Abstract
    In this paper, we consider the bacterial point-to-point communication problem with one transmitter and one receiver by considering the ligand receptor binding process. The most commonly investigated signalling model, referred to as the Level Scenario (LS), uses one type of a molecule with different concentration levels for signaling. An alternative approach is to employ multiple types of molecules with a single concentration level, referred to as the Type Scenario (TS). We investigate the trade-offs between the two scenarios for the ligand receptor from the capacity point of view. For this purpose, we evaluate the capacity using numerical algorithms. Moreover, we derive an upper bound on the... 

    Physical layer network coding in molecular two-way relay networks

    , Article IWCIT 2016 - Iran Workshop on Communication and Information Theory, 3 May 2016 through 4 May 2016 ; 2016 ; 9781509019229 (ISBN) Farahnak Ghazani, M ; Aminian, G ; Mirmohseni, M ; Gohari, A ; Nasiri Kenari, M ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2016
    Abstract
    In traditional wireless networks, physical layer network coding (PNC) exploits the inverse additivity property of broadcast signals in the medium, an idea which is not directly applicable to molecular networks. In this paper, to make the natural XOR operation possible at the physical layer, we exploit the reaction of different molecule types and we propose a PNC scheme in diffusion-based molecular relay networks. For comparison, we consider the straightforward network coding (SNC) scheme in molecular networks. Assuming the ligand-receptor binding process at the receivers, we investigate the error performance of both schemes. It is observed that in addition to the simplicity of the proposed... 

    Modeling of an ultrasound system in targeted drug delivery to abdominal aortic aneurysm: a patient-specificin silico study based on ligand-receptor binding

    , Article IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control ; Volume 69, Issue 3 , 2022 , Pages 967-974 ; 08853010 (ISSN) Shamloo, A ; Boroumand, A ; Ebrahimi, S ; Kalantarnia, F ; Maleki, S ; Moradi, H ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2022
    Abstract
    Targeted drug delivery methods have shown a significant impact on enhancing drug delivery efficiency and reducing drug side effects. While various stimuli have been used to promote the drug delivery process, applying ultrasound (US) waves to control drug particles through the human body, noninvasively, has drawn the scientist's attention. However, microcarriers delivery reaches the aneurysmal artery by US waves that exert volumetric forces on blood, and drug carriers, which can therefore affect blood flow patterns and movement pathways of drug carriers, have not yet been studied. In this study, we developed a 3-D patient-specific model of abdominal aortic aneurysm (AAA) to evaluate the... 

    Targeted drug delivery of magnetic microbubble for abdominal aortic aneurysm: an in silico study

    , Article Biomechanics and Modeling in Mechanobiology ; Volume 21, Issue 2 , 2022 , Pages 735-753 ; 16177959 (ISSN) Shamloo, A ; Ebrahimi, S ; Ghorbani, G ; Alishiri, M ; Sharif University of Technology
    Springer Science and Business Media Deutschland GmbH  2022
    Abstract
    Targeted drug delivery (TDD) to abdominal aortic aneurysm (AAA) using a controlled and efficient approach has recently been a significant challenge. In this study, by using magnetic microbubbles (MMBs) under a magnetic field, we investigated the MMBs performance in TDD to AAA based on the amount of surface density of MMBs (SDMM) adhered to the AAA lumen. The results showed that among the types of MMBs studied in the presence of the magnetic field, micromarkers are the best type of microbubble with a −50 % increase in SDMM adhered to the critical area of AAA. The results show that applying a magnetic field causes the amount of SDMM adhered to the whole area of AAA to increase −1.54 times...