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lithium-derivative
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Highly diastereoselective aminoalkylation of naphthols with chiral amines mediated by lithium perchlorate solution in diethyl ether
, Article Tetrahedron Asymmetry ; Volume 14, Issue 3 , 2003 , Pages 389-392 ; 09574166 (ISSN) ; Azizi, N ; Sharif University of Technology
2003
Abstract
One-pot, three-component, Mannich reaction of naphthols with in situ prepared imines in 5 M ethereal lithium perchlorate at room temperature affords the corresponding aminoalkylated products in high yields with high diastereoselectivities. The process is exemplified by the reaction of 2-naphthol with (R)-1-phenylethylamine and an aromatic aldehyde in concentrated ethereal lithium perchlorate solution, which affords a highly diastereoselective access to the requisite 2-aminoalkylated product. © 2003 Elsevier Science Ltd. All rights reserved
A cheap, simple, and versatile method for acetylation of alcohols and phenols and selective deprotection of aromatic acetates under solvent-free condition
, Article Synthetic Communications ; Volume 35, Issue 3 , 2005 , Pages 483-491 ; 00397911 (ISSN) ; Saidi, M. R ; Sharif University of Technology
2005
Abstract
Acyclic and cyclic acetates of various alcohols and phenols were obtained in excellent yields under mild reaction conditions in the presence of a catalytic amount of sodium hydroxide under solvent-free conditions and microwave irradiation. Selective deprotection of acetate group from the corresponding phenolic compounds was carried out in the presence of LiClO4· 2H2O. Copyright © Taylor & Francis, Inc