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Simulation of Paramecium Chemotaxis Exposed to Calcium Gradients
, Article Cell Biochemistry and Biophysics ; Volume 74, Issue 2 , 2016 , Pages 241-252 ; 10859195 (ISSN) ; Shamloo, A ; Ahmadian, M. T ; Sharif University of Technology
Humana Press Inc
2016
Abstract
Paramecium or other ciliates have the potential to be utilized for minimally invasive surgery systems, making internal body organs accessible. Paramecium shows interesting responses to changes in the concentration of specific ions such as K+, Mg2+, and Ca2+ in the ambient fluid. Some specific responses are observed as, changes in beat pattern of cilia and swimming toward or apart from the ion source. Therefore developing a model for chemotactic motility of small organisms is necessary in order to control the directional movements of these microorganisms before testing them. In this article, we have developed a numerical model, investigating the effects of Ca2+ on swimming trajectory of...
Simulation of Paramecium Swimming in an Environment with a Chemical Gradient
, M.Sc. Thesis Sharif University of Technology ; Ahmadian, Mohammad Taghi (Supervisor) ; Shamloo, Amir (Supervisor)
Abstract
In the recent decade, researchers in the field of minimally invasive medicine have come up to the idea of utilizing micro organisms as smart micro robots. The advantage with this idea is the fact that problems such as energy supply and maneuvering are resolved for these sorts of micro swimmers. In this current work, a new numerical method for investigation of micro swimming is developed which is computationally efficient in characterizing locomotion of micro swimmers and using a finite element method software, locomotion of Paramecium has been investigated inside and outside a capillary tube. According to simulation results, it is possible to design a controlling system which is capable of...
Active microfluidic micromixer design using ionic polymer-metal composites
, Article 27th Iranian Conference on Electrical Engineering, ICEE 2019, 30 April 2019 through 2 May 2019 ; 2019 , Pages 371-375 ; 9781728115085 (ISBN) ; Mohammadzadeh, H ; Aghassizadeh, A ; Azizmohseni, S ; Fardmanesh, M ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2019
Abstract
In most of the microfluidic applications, it is necessary to have a mixed fluid from the beginning, but in microchannels, due to facing with low Reynolds flows, the fluids flow in the channel by the laminar regimes. Hence the mixing process is a challenging problem and researchers are trying to present fast and reliable micromixers. In this paper, using Ionic Polymer-Metal Composites (IPMCs), an active micromixer has been designed. To investigate the appropriateness of IPMC, using experimental and simulation tests, we show that the IPMC actuator is a potential candidate as an active element of microfluidic micromixers
Multiphysics analysis and practical implementation of a soft μ-actuator- based microfluidic micromixer
, Article Journal of Microelectromechanical Systems ; Volume 29, Issue 2 , 2020 , Pages 268-276 ; Azizmohseni, S ; Esmaeili Dokht, P ; Bagheri, N ; Aghassizadeh, A ; Fardmanesh, M ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2020
Abstract
Electroactive-Polymers (EAPs) are one of the best soft $mu $ -actuators with great biomedical applications. Ionic ones (i-EAPs) have more promising features and have adequate potential for using in the active microfluidic devices. Here, as a case study, we have designed and fabricated a microfluidic micromixer using an i-EAP named Ionic Polymer-Metal Composite (IPMC). In microfluidics, active devices have more functionality but due to their required facilities are less effective for Point of Care Tests (POCTs). In the direction of solving this paradox, we should use some active components that they need minimum facilities. IPMC can be one of these components, hence by integrating the IPMC...