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Iron oxyhydroxide nanoparticles: green synthesis and their cytotoxicity activity against A549 human lung adenocarcinoma cells
, Article Rendiconti Lincei ; Volume 33, Issue 2 , 2022 , Pages 461-469 ; 20374631 (ISSN) ; Alijani, H. Q ; Hashemi Shahraki, S ; Naderifar, M ; Rahimi, S. S ; Abolhasani Zadeh, F ; Iravani, S ; Haghighat, M ; Khatami, M ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2022
Abstract
Iron oxyhydroxide (α-FeOOH, Goethite) is one of the most thermodynamically stable iron oxides and a widespread soil mineral. In this study, a mixture of two phenolic extracts of rosemary and Echinacea was utilized as stabilizing and reducing agents for the synthesis of Goethite (FeOOH) nanoparticles without utilizing harmful toxic solvents. The resulting nanoparticles were characterized by X-ray powder diffraction (XRD), field emission scanning electron microscopy (FESEM)-energy dispersive spectroscopy (EDS), transmission electron microscopy (TEM), vibrating-sample magnetometer (VSM), thermogravimetry/differential thermal analysis (TG/DTA), and Brunauer–Emmett-Teller (BET). MTT assay was...
Recent advances in porphyrin-based nanocomposites for effective targeted imaging and therapy
, Article Biomaterials ; Volume 232 , 2020 ; Tavakkoli Yaraki, M ; Mokhtari Garakani, S ; Mokhtari Garakani, S ; Ahmadi, S ; Lajevardi, A ; Bagherzadeh, M ; Rabiee, M ; Tayebi, L ; Tahriri, M ; Hamblin, M. R ; Sharif University of Technology
Elsevier Ltd
2020
Abstract
Porphyrins are organic compounds that continue to attract much theoretical interest, and have been called the “pigments of life”. They have a wide role in photodynamic and sonodynamic therapy, along with uses in magnetic resonance, fluorescence and photoacoustic imaging. There is a vast range of porphyrins that have been isolated or designed, but few of them have real clinical applications. Due to the hydrophobic properties of porphyrins, and their tendency to aggregate by stacking of the planar molecules they are difficult to work with in aqueous media. Therefore encapsulating them in nanoparticles (NPs) or attachment to various delivery vehicles have been used to improve delivery...