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Design, Simulation and Construction of a Microfluidic Device for the Purpose of Target Cells Separation and DNA Extraction
, M.Sc. Thesis Sharif University of Technology ; Shamloo, Amir (Supervisor) ; Nouri Borujerdi, Ali (Supervisor)
Abstract
Today, microfluidic experiments have found wide applications in medical sciences, engineering, and chemistry. Because of their small size, microfluidic devices help us to be able to use very little amount of sample for the experiments and also easily control and observe the under-experiment fluid. One of the most important applications of these devices is the separation of cancer cells in blood for counting their number and DNA genetic studies. In the current project we have tried to do the separation of cancer cells from other cells by designing an inertia microchannel. For this purpose, in the first step a geometry for the channel is designed with analyzing the induced forces on the cells....