Sharif Digital Repository

Superparamagnetic iron oxide nanoparticles (SPIONs) are promising materials for various biomedical applications including targeted drug delivery and imaging, hyperthermia, magneto-transfections, gene therapy, stem cell tracking, molecular/cellular tracking, magnetic separation technologies (e.g. rapid DNA sequencing), and detection of liver and lymph node metastases. The most recent applications for SPIONs for early detection of inflammatory, cancer, diabetes and atherosclerosis have also increased their popularity in academia. In order to increase the efficacy of SPIONs in the desired applications, especial surface coating/characteristics are required. The aim of this article is to review... 

Superparamagnetic iron oxide nanoparticles (SPIONs) are promising materials for various biomedical applications including targeted drug delivery and imaging, hyperthermia, magneto-transfections, gene therapy, stem cell tracking, molecular/cellular tracking, magnetic separation technologies (e.g. rapid DNA sequencing), and detection of liver and lymph node metastases. The most recent applications for SPIONs for early detection of inflammatory, cancer, diabetes and atherosclerosis have also increased their popularity in academia. In order to increase the efficacy of SPIONs in the desired applications, especial surface coating/characteristics are required. The aim of this article is to review... 

An investigation into the addition of different weight percentages of Fe3O4 nanoparticles to find the optimum wt.% and its effect on the microstructure, thermal, magnetic, and electrical properties of aluminum matrix composite was conducted using the powder metallurgy method. The purpose of this research was to develop magnetic properties in aluminum. Based on the obtained results, the value of density, hardness, and saturation magnetization (Ms) from 2.33 g/cm3, 43 HV and 2.49 emu/g for Al-10 Fe3O4 reached a maximum value of 3.29 g/cm3, 47 HV and 13.06 emu/g for the Al-35 Fe3O4 which showed an improvement of 41.2%, 9.3%, and 424.5%, respectively. The maximum and minimum coercivity (Hc) was... 

In the present research, iron oxide nanoparticles were synthesized through the hydrothermal method, and the influence of processing parameters such as pH of the initial coprecipitation reaction, time and temperature of hydrothermal treatment was studied. The magnetic iron oxide nanoparticles were coated with a negatively charged, thin layer of silica. The product is then coated with a layer of mesoporous silica. As a result of the electrostatic attraction between the cationic CTAB and the primary silica coating, the formation of mesoporous silica would be mainly localized on the surface of nanoparticles. Calcination was performed in an argon atmosphere tube furnace at 550 °C, through which... 

Cancer is a deadly disease that has long plagued humans and has become more prevalent in recent years. The common treatment modalities for this disease have always faced many problems and complications, and this has led to the discovery of strategies for cancer diagnosis and treatment. The use of magnetic nanoparticles in the past two decades has had a significant impact on this. One of the objectives of the present study is to introduce the special properties of these nanoparticles and how they are structured to load and transport drugs to tumors. In this study, iron oxide (Fe3O4) nanoparticles with 6 nm sizes were coated with hyperbranched polyglycerol (HPG) and folic acid (FA). The...