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    A Mechanobiological model for damage-induced growth in arterial tissue with application to in-stent restenosis

    , Article Journal of the Mechanics and Physics of Solids ; Volume 101 , 2017 , Pages 311-327 ; 00225096 (ISSN) Fereidoonnezhad, B ; Naghdabadi, R ; Sohrabpour, S ; Holzapfel, G. A ; Sharif University of Technology
    Elsevier Ltd  2017
    In-stent restenosis (ISR) is one of the main drawbacks of stent implementation which limits the long-term success of the procedure. Morphological changes occurring within the arterial wall due to stent-induced mechanical injury are a major cause for activation of vascular smooth muscle cells (VSMCs), and the subsequent development of ISR. Considering the theory of volumetric mass growth and adopting a multiplicative decomposition of the deformation gradient into an elastic part and a growth part, we present a mechanobiological model for ISR. An evolution equation is developed for mass growth of the neointima, in which the activation of VSMCs due to stent-induced damage (injury) and the... 

    CFD-aided simulation of frost growth inside a narrow duct with uniform wall temperature variation

    , Article ASME 2014 12th International Conference on Nanochannels, Microchannels, and Minichannels, ICNMM 2014, Collocated with the ASME 2014 4th Joint US-European Fluids Engineering Division Summer Meeting ; 2014 ; ISBN: 9780791846278 Darbandi, M ; Asgari, E ; Hajikaram, M ; Schneider, G. E ; Sharif University of Technology
    In this paper, we study the frost formation and growth at the walls of a duct with uniform wall temperature variation. The simulation is performed for laminar flow regime considering suitable semi-empirical models incorporated with computational fluid dynamics (CFD) method. The frost growth is considered to be normal to the duct surface. Since the duct aspect ratio is high, we perform our simulations in two-dimensional zones. To simulate the frost layer properly, we solve both the energy and mass balance equations implementing some semi-empirical correlations on the frost side. At this stage, we suitably predict the required heat flux value at the solid boundary and the heat transfer... 

    Optimization assisted asphaltene deposition modeling in porous media during a natural depletion scheme

    , Article Petroleum Science and Technology ; Volume 30, Issue 9 , Mar , 2012 , Pages 958-965 ; 10916466 (ISSN) Hematfar, V ; Bagheri, M ; Kharrat, R ; Ghazanfari, M ; Ghotbi, C ; Sharif University of Technology
    Changes in thermodynamic properties such as pressure, temperature, and composition may result in asphaltene precipitation and deposition in porous media. In addition, asphaltene deposition can cause wettability alteration, permeability reduction, and ultimately a decrease in the productivity of a reservoir. Natural depletion is one of the most common processes of asphaltene deposition in which pressure changes destabilize the dissolved asphaltene in the oil and settle them onto the rock surface. In this work, natural depletion experiments in consolidated core samples were performed under simulated reservoir conditions to obtain reliable data and analyze the asphaltene deposition mechanisms.... 

    Modeling and optimization of asphaltene deposition in porous media using genetic algorithm technique

    , Article Society of Petroleum Engineers - International Oil and Gas Conference and Exhibition in China 2010, IOGCEC, 8 June 2010 through 10 June 2010 ; Volume 1 , June , 2010 , Pages 479-491 ; 9781617388866 (ISBN) Hematfar, V ; Kharrat, R ; Ghazanfari, M. H ; Bagheri, M. B ; Sharif University of Technology
    Different models have been proposed for deposition of asphaltene on reservoir rocks that due to complexity of asphaltene nature, most of them have not been productive. Here, a reliable model is proposed which despite of previous models, considers the change in asphaltene saturation in the core. The obtained experimental data in the laboratory was used for model validation. In this work, a series of core flooding tests was carried out in presence of connate water at different solvent-oil volume ratios. Pressure drop was measured at three different terminals along the core. The obtained experimental data as well as mass balance equations, momentum equation, asphaltene deposition and... 

    Dynamic modeling and optimization of asphaltene deposition in reservoir rocks using genetic algorithm

    , Article 72nd European Association of Geoscientists and Engineers Conference and Exhibition 2010: A New Spring for Geoscience. Incorporating SPE EUROPEC 2010 ; Volume 6 , 2010 , Pages 4291-4295 ; 9781617386671 (ISBN) Bagheri, M. B ; Kharrat, R ; Hemmatfar, V ; Ghotbi, C ; Sharif University of Technology
    Society of Petroleum Engineers  2010
    Asphaltene deposition is a problematic challenge for oil production. Changes in key parameters like pressure and fluid composition during natural depletion and different gas injection scenarios may result in asphaltene precipitation and deposition. In this work, a model is developed by application of mass balance equations, momentum equation, asphaltene deposition and permeability reduction models. An algorithm is developed to perform iterative procedure to solve the numerical equations that contains highly coupled variables. Indeed, an equation is introduced to calculate the saturation of the precipitated asphaltene phase. Model parameters were determined by genetic algorithm which is a... 

    Hydro-mechanical modeling of two-phase fluid flow in deforming, partially saturated porous media with propagating cohesive cracks using the extended finite element method

    , Article Computational Plasticity XI - Fundamentals and Applications, COMPLAS XI, 7 September 2011 through 9 September 2011 ; September , 2011 , Pages 1516-1527 ; 9788489925731 (ISBN) Mohammadnejad, T ; Khoei, A. R ; Sharif University of Technology
    In the present paper, a fully coupled numerical model is developed for the hydromechanical analysis of deforming, progressively fracturing porous media interacting with the flow of two immiscible, compressible wetting and non-wetting pore fluids. The governing equations involving the coupled two-phase fluid flow and deformation processes in partially saturated porous media containing cohesive cracks are derived within the framework of the generalized Biot theory. The displacement of the solid phase, the pressure of the wetting phase and the capillary pressure are taken as the primary unknowns of the three-phase formulation. A softening cohesive law is employed to describe the nonlinear...