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matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry
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Poly(citric acid)-block-poly(ethylene glycol) copolymers-new biocompatible hybrid materials for nanomedicine
, Article Nanomedicine: Nanotechnology, Biology, and Medicine ; Volume 6, Issue 4 , Aug , 2010 , Pages 556-562 ; 15499634 (ISSN) ; Adeli, M ; Vossoughi, M ; Sharif University of Technology
Abstract
Linear-dendritic ABA triblock copolymers containing poly(ethylene glycol) (PEG) as B block and hyperbranched poly(citric acid) (PCA) as A blocks were synthesized through polycondensation. The molecular self-assembly of synthesized PCA-PEG-PCA copolymers in water led to formation of nanoparticles and fibers in different sizes and shapes depending on the time and size of PCA blocks. Ten days after dissolving PCA-PEG-PCA copolymers in water, the size of fibers had reached several millimeters. Mixing a water solution of fluorescein as a small guest molecule and PCA-PEG-PCA copolymers led to the encapsulation of fluorescein by products of molecular self-assembly. To investigate their potential...