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    Amine modified magnetic polystyrene for extraction of drugs from urine samples

    , Article Journal of Chromatography A ; Volume 1602 , 2019 , Pages 107-116 ; 00219673 (ISSN) Zeinali, S ; Maleki, M ; Bagheri, H ; Sharif University of Technology
    Elsevier B.V  2019
    Abstract
    Polystyrene is one of the best candidates as the extracting medium due to its high stability in different media and acceptable extraction capability. However, the hydrophobic nature and low wettability of polystyrene limits its application to non–polar analytes. To resolve this limitation, in this project, amine groups were chemically attached to the surface of magnetic polystyrene. The resulting hydrophilic magnetic particles were expected to be capable of extracting both polar and non–polar analytes. Non–steroidal anti–inflammatory drugs (NSAIDs) were chosen for testing the applicability of modified magnetic polystyrene according to the importance of their analysis and also their wide... 

    Generic extraction medium: From highly polar to non-polar simultaneous determination

    , Article Analytica Chimica Acta ; Volume 1066 , 2019 , Pages 1-12 ; 00032670 (ISSN) Zeinali, S ; Khalilzadeh, M ; Bagheri, H ; Sharif University of Technology
    Elsevier B.V  2019
    Abstract
    Sample preparation for non-target analysis is challenging due to the difficulty in the extraction of polar and non-polar analytes simultaneously. Most commercial solid sorbents lack the proper comprehensiveness for extraction of analytes with different physiochemical properties. A possible key is the combination of hydrophobic polymer and hydrophilic surface functional groups in solid based extraction methods in order to generate the susceptibility for retaining both polar and non-polar analytes. To pursue this goal, in this study, four polar groups including [sbnd]NH 2 , [sbnd]NO 2 , [sbnd]COOH, and [sbnd]COCH 3 were chemically bound to Amberlite XAD-4 substrate in order to prepare a... 

    Design and fabrication of an electrochemical aptasensor using Au nanoparticles/carbon nanoparticles/cellulose nanofibers nanocomposite for rapid and sensitive detection of Staphylococcus aureus

    , Article Bioelectrochemistry ; Volume 123 , 2018 , Pages 70-76 ; 15675394 (ISSN) Ranjbar, S ; Shahrokhian, S ; Sharif University of Technology
    Elsevier B.V  2018
    Abstract
    Since that pathogenic bacteria are major threats to human health, this paper describes the fabrication of an effective and durable sensing platform based on gold nanoparticles/carbon nanoparticles/cellulose nanofibers nanocomposite (AuNPs/CNPs/CNFs) at the surface of glassy carbon electrode for sensitive and selective detection of Staphylococcus aureus (S. aureus). The AuNPs/CNPs/CNFs nanocomposite with the high surface area, excellent conductivity, and good biocompatibility was used for self-assembled of the thiolated specific S. aureus aptamer as a sensing element. The surface morphology of AuNPs/CNPs/CNFs nanocomposite was characterized with field emission scanning electron microscopy...