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    Measuring viscoelastic properties of Red Blood Cell using optical tweezers

    , Article Iranian Journal of Physics Research ; Volume 19, Issue 1 , 2019 , Pages 101-108 ; 16826957 (ISSN) Seyed Reihani, S. N ; Azadbakht, A ; Mirzahossein, E ; Mottaghian, M ; Babaei, M ; Sharif University of Technology
    Isfahan University of Technology  2019
    Abstract
    Efforts have been made to study the behavior of complex materials in micrometer dimensions with various techniques. One of these methods is the use of optical tweezers for biophysical applications. Red blood cells, as the most abundant blood-forming cells, play an important role in the life of living organisms, and their unique mechanical properties are important. In this report, the study of soft materials is done using light tweezers. This work investigates micrometer particle movements in the optical trap and also, when they are connected to a red blood cell. The tweezers allow the Newtonian fluid viscosity, such as water and glycerin, to measure the mechanical properties of viscoelastic... 

    Measuring viscoelastic properties of Red Blood Cell using optical tweezers

    , Article Iranian Journal of Physics Research ; Volume 19, Issue 1 , 2019 , Pages 101-108 ; 16826957 (ISSN) Seyed Reihani, S. N ; Azadbakht, A ; Mirzahossein, E ; Mottaghian, M ; Babaei, M ; Sharif University of Technology
    Isfahan University of Technology  2019
    Abstract
    Efforts have been made to study the behavior of complex materials in micrometer dimensions with various techniques. One of these methods is the use of optical tweezers for biophysical applications. Red blood cells, as the most abundant blood-forming cells, play an important role in the life of living organisms, and their unique mechanical properties are important. In this report, the study of soft materials is done using light tweezers. This work investigates micrometer particle movements in the optical trap and also, when they are connected to a red blood cell. The tweezers allow the Newtonian fluid viscosity, such as water and glycerin, to measure the mechanical properties of viscoelastic... 

    Study of Viscoelastic Properties of Biopolymer Solutions

    , M.Sc. Thesis Sharif University of Technology Shahmoradi, Mohammad Reza (Author) ; Seyed Reihani, Nader (Supervisor)
    Abstract
    Properties of viscoelastic of biopolymers have important role in cells structure; for example: cell motility depends on viscoelastic propertie of Actin polymer. therefore according to its importance ,in this thesis we intend to examine the viscoelastic modulus using Optical tweezers and dissipation theorem.this method is benefits than methods of active microrheology. for example this method can be used for low concentrations; because in the low concentrations, the exerting force will cause changing in the state of matter that here we investigate destructive force effect. we investigate viscoelastic of water for method accuracy then obtain viscoelastic of Kelcogel  

    Electric-field-induced response of a droplet embedded in a polyelectrolyte gel

    , Article Physics of Fluids ; Volume 25, Issue 8 , 2013 ; 10706631 (ISSN) Mohammadi, A ; Sharif University of Technology
    2013
    Abstract
    The electric-field induced response of a droplet embedded in a quenched polyelectrolyte gel is calculated theoretically. The response comprises the droplet translation and the electric-field induced flow fields within the droplet. The gel is modeled as a soft, and electrically charged porous solid saturated with a salted Newtonian fluid. The droplet is considered an incompressible Newtonian fluid with no free charge. An analytical solution, using the perturbation methodology and linear superposition, is obtained for the leading-order steady response to a DC electric-field. The fluid within the droplet is driven due to hydrodynamic coupling with the electroosmotic flow. The fluid velocity... 

    Dynamical time scales of friction dynamics in active microrheology of a model glass

    , Article Soft Matter ; Volume 17, Issue 20 , 2021 , Pages 5162-5169 ; 1744683X (ISSN) Madanchi, A ; Yu, J. W ; Lee, W. B ; Rahimi Tabar, M. R ; Rahbari, S. H. E ; Sharif University of Technology
    Royal Society of Chemistry  2021
    Abstract
    Owing to the local/heterogeneous structures in supercooled liquids, after several decades of research, it is now clear that supercooled liquids are structurally different from their conventional liquid counterparts. Accordingly, an approach based on a local probe should provide a better understanding about the local mechanical properties as well as heterogeneous structures. Recently, the superiority of active microrheology over global rheology has been demonstrated [Yu et al., Sci. Adv., 2020, 6, 8766]. Here, we elaborate this new avenue of research and provide more evidence for such superiority. We report on the results of an extensive molecular dynamics simulation of active microrheology... 

    Design and Optimization of an Intelligent Impedance-based Flow Cytometer for POCT Applications

    , M.Sc. Thesis Sharif University of Technology Meskar, Zahra (Author) ; Fardmanesh, Mehdi (Supervisor) ; Annabestani, Mohsen (Co-Supervisor)
    Abstract
    Microfluidics is the science of fabricating systems interfacing fluids of small volume and size ranging from microliters (10-6) to picolitres (10-12). Due to its remarkable features, such as low sample and reagent consumption, high sensitivity, low cost, automated devices, and short experimental time, microfluidic chips have been widely used as laboratory assays. As a term often used and described in “lab on a chip” and “organ on a chip” technologies, microfluidic chips have been used in the fast and frugal diagnosis of infectious diseases such as HIV, microscale surgery on single cells and tiny organisms and cell culture.The design, simulation, optimization, and fabrication of an...