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Modeling and analytical solution of hybrid thermopiezoelectric micro actuator and performance study under changing of different parameters
, Article Mechanics of Advanced Materials and Structures ; Volume 22, Issue 10 , Mar , 2015 , Pages 785-793 ; 15376494 (ISSN) ; Kargarnovin, M. H ; Zohoor, H ; Sharif University of Technology
Taylor and Francis Inc
2015
Abstract
Micro actuators are an irreplaceable part of motion control in miniaturized systems and are intended to have a high range of deformation, high accuracy, large force, and quick response. In this article, an analytical model for a hybrid thermopiezoelectric micro actuator is developed in which a double lead-zirconnate-titanate piezoceramic (PZT) beam structure consisting of two arms with different lengths are used. Governing differential equation of motion and electrical field are derived and solved. Out of parametric studies it was observed that, under application of temperature and voltage gradients, the deflection of the actuator shows different trends depending on the geometry of the micro...
Modeling, simulation, and employing dilution–dialysis microfluidic chip (DDMC) for heightening proteins refolding efficiency
, Article Bioprocess and Biosystems Engineering ; Volume 41, Issue 5 , 2018 , Pages 707-714 ; 16157591 (ISSN) ; Masoudi, M. M ; Shamloo, A ; Habibi Rezaei, M ; Moosavi Movahedi, A. A ; Sharif University of Technology
Springer Verlag
2018
Abstract
Miniaturized systems based on the principles of microfluidics are widely used in various fields, such as biochemical and biomedical applications. Systematic design processes are demanded the proper use of these microfluidic devices based on mathematical simulations. Aggregated proteins (e.g., inclusion bodies) in solution with chaotropic agents (such as urea) at high concentration in combination with reducing agents are denatured. Refolding methods to achieve the native proteins from inclusion bodies of recombinant protein relying on denaturant dilution or dialysis approaches for suppressing protein aggregation is very important in the industrial field. In this paper, a modeling approach is...