Sharif Digital Repository

The importance of hyperthermia as a promising method in disruption and removal of cancerous cells is well understood. One of the effective options of concentration of heat within a specific tissue is using laser and exploiting absorption properties of metallic nanostructures. In this report, the geometrical effect of gold nanostructures in the performance of laser based hyperthermia has been analyzed. The analysis is based on the consideration of absorption properties of gold nanostructures, interaction of laser light with a specific tissue containing nanostructures and the effect of generated heat on elevation of temperature inside the tissue. The analysis is performed using Mie theory (for... 

This research presents an application of transparent lanthanum-modified lead zirconate titanate (PLZT) materials in micro light source tracking device, which is designed to function as a result of irradiation, having neither lead wires nor electric circuits. The focus of the paper is on the analytical and finite element investigation into ultraviolet photo-induced multi-physics responses of PLZT photocantilever and a comparison of the measured bending displacement to check the feasibility of these materials in design of micro light source tracking device. The finite element formulation of the transverse deflection for multi-physics analysis of PLZT ceramics by including the photovoltaic and... 

Exploiting of the nanostructure arrays as a promising candidate for excitation of neural cells has been analyzed. Based on the importance of the coupling effect between electrode and neuron, a multiphyscis modeling approach has been proposed. The model incorporates theoretically both structural effects (size, geometry) and electrophysiological effects. The system of equations for proposed model has been solved numerically using Finite Element Method for Poisson equation and Finite Difference Method for Cable equation. In this regards we have combined the system of equations in COMSOL platform with Matlab interface accordingly. We have analyzed the effect of excitation of neuron with an extra... 

Multielectrode array (MEA) structures are the vital parts in the interface between neural structures and external electronic circuits, both in excitation and detection. As a transducer, the performance of electrodes has direct effect on the quality of the recorded neural signal, as well as induced charge density during the stimulation in neural prosthesis. The size and geometry of the electrode structure have distinct effect on the performance of electrodes accordingly. In this paper, the effect of size and geometry of the electrodes has been investigated in their performance and the impedimetric features of the fabricated electrodes with different structures have been studied. Based on the... 

Electroactive-Polymers (EAPs) are one of the best soft $mu $ -actuators with great biomedical applications. Ionic ones (i-EAPs) have more promising features and have adequate potential for using in the active microfluidic devices. Here, as a case study, we have designed and fabricated a microfluidic micromixer using an i-EAP named Ionic Polymer-Metal Composite (IPMC). In microfluidics, active devices have more functionality but due to their required facilities are less effective for Point of Care Tests (POCTs). In the direction of solving this paradox, we should use some active components that they need minimum facilities. IPMC can be one of these components, hence by integrating the IPMC... 

This article is the first attempt to employ deep learning to estimate the frequency performance of the rotating multi-layer nanodisks. The optimum values of the parameters involved in the mechanism of the fully connected neural network are determined through the momentum-based optimizer. The strength of the method applied in this survey comes from the high accuracy besides lower epochs needed to train the multi-layered network. It should be mentioned that the current nanostructure is modeled as a nanodisk on the viscoelastic substrate. Due to rotation, the centrifugal and Coriolis effects are considered. Hamilton’s principle and generalized differential quadrature method (GDQM) are presented... 

In puffer type Sulfur Hexafluoride (SF6) Circuit Breakers (CBs), the refill valve is the main inlet duct for the SF6 gas to enter the puffer volume. When the CB is closing and moving contacts and the nozzle are moving toward fixed contacts, the SF6 gas enters the puffer volume via the refill valve. Since changing the refill valve diameter can alter the direction of the SF6 gas motion in the closing operation of CBs, understanding its effects on CBs' function and performance may help to improve the CB design. This paper has focused on the effects of refill valve diameter on prestrike occurrence in the closing operation of puffer type SF6 CBs. In order to accurately study these effects, some... 

In this paper, an alternative way of harvesting energy from ambient vibration is investigated through proposing a novel inertial energy harvester using magnetic shape memory alloys (MSMAs). To this end, a clamped-clamped beam is coupled with MSMA units which are attached to its roots. A shock load is applied to a proof mass in the middle of the beam. The beam vibration causes longitudinal strain in the MSMAs and as a result the magnetic flux alters in the coils wounding around the MSMA units and produce an AC voltage. To have a reversible strain in MSMAs, a bias magnetic field is applied in transverse direction of the MSMA units. The large scale vibration of Euler-Bernoulli beam is modeled... 

Electrohydrodynamic (EHD) printing is a novel technology used for fabricating high-resolution part features from a wide range of materials. Due to the multiphysics dynamics and the multiphase nature of the microdroplet formation in the EHD printers, modeling of this phenomenon is complicated. In this paper, the formation of a droplet in an EHD printer—under a pulsed electrical field—is simulated using a new numerical model which couples the fluid flow, the electric field distribution and the movement of the electric charges under dynamic and transient conditions. The level-set method is applied to the entire multiphysics domain in order to study the formation of the droplet. The presented... 

Natural gas hydrate, a crystalline solid existing under high-pressure and low-temperature conditions, has been regarded as a potential alternative energy resource. It is globally widespread and occurs mainly inside the pores of deepwater sediments and sediments under permafrost area. Hydrate production via well depressurization is deemed well-suited to existing technology, in which the pore pressure is lowered, the natural gas hydrate is dissociated into water and gas, and the water and gas are produced from well. This method triggers multiphysics processes such as fluid flow, heat transfer, energy adsorption, chemical reaction and sediment deformation, all of which are dependent on the... 

Induced Polarization (IP) is a non-intrusive geophysical method to monitor Dense Non-Aqueous Phase Liquid (DNAPL) contamination and remediation processes underground. In this study, an advanced numerical code simulating DNAPL flow and complex electrical resistivity is presented. The model was validated against existing IP results and image measurements that were carried out previously in a series of 2D tank experiment. Multiphase flow modeling in porous media is coupled with electrical current modeling to simulate the process of DNAPL migration and the associated IP response. This brings a broader view of the contamination in space and time compared to surface and borehole measurements,... 

This study investigated the behavior of ferrofluids containing superparamagnetic iron oxide nanoparticles (SPION) of various compositions for potential applications in drug delivery and imaging. To ensure biocompatibility, the interaction of these SPION with two cell lines (adhesive and suspended) was also investigated using an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide) assay. The cell lines studied were primary mouse connective tissue cells (adhesive) and human leukemia cells (suspended). SPION were synthesized with a co-precipitation method under different stirring rates and NaOH molarities. The SPION demonstrated a range of magnetic saturations due to their...