Sharif Digital Repository

Nowadays, many manufacturing and service systems provide products and services to their customers in several consecutive stages of operations, in each of which one or more quality characteristics of interest are monitored. In these environments, the final quality in the last stage not only depends on the quality of the task performed in that stage but also is dependent on the quality of the products and services in intermediate stages as well as the design parameters in each stage. In this paper, a novel methodology based on the posterior preference approach is proposed to robustly optimize these multistage processes. In this methodology, a multi-response surface optimization problem is... 

In this study, QuEChERS combined with dispersive liquid-liquid microextraction is developed for extraction of ten pesticides in complex sample matrices of water and milk. In this regard, effective factors of proposed extraction technique combined with gas chromatography with flame ionization detector were designed, modeled, and optimized using central composite design, multiple linear regression, and Nelder–Mead simplex optimization. Later, univariate calibration model for ten pesticides was developed in concentration range of 0.5–100 ng/mL. Surprisingly, quadratic calibration behavior was observed for some of the pesticides. In this regard, Mandel's test was used for evaluating linearity...