Sharif Digital Repository

Building complex and functional tissues and organs is very challenging. One of the challenges is building an efficient network of blood vessels that can be used to facilitate the transport of nutrients and oxygen to the host. In addition to using channels for oxygen supply, another solution is to use oxygen-carrying materials. In this study, in addition to designing and simulating scaffolds with multi-scale microchannels, calcium peroxide was used to release oxygen and eliminate hypoxia in the scaffold. Here alginate is used as the main material for scaffolding. In an attempt to build a scaffold using a bio-printer, pluronic acid was also used as a sacrificial material to create canals....