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    Simulation of Competitive Flow in the Coronary Arteries Bypass

    , M.Sc. Thesis Sharif University of Technology Azimi Nejad, Milad (Author) ; Firoozabadi, Bahar (Supervisor)
    Atherosclerosis is one of the most important factors for mortality and morbidity in the world. Coronary artery bypass graft (CABG) is applied for treatment of this disease which in this surgery, the patient vessels, such as internal thoracic artery and saphenous vein, are harvested and grafted to the coronary arteries. The graft success and its performance in short and long-term are depended on the much factors e.g. the severity of stenosis in the coronary artery. It should be noted that the low level of stenosis in the coronary artery causes the creation of undesirable phenomenon of competitive flow in the grafts after the surgery which this phenomenon has been reported as a cause of graft... 

    Computational simulation of non-Newtonian blood flow in carotid bifurcation for investigation the various rheological blood models

    , Article ASME 2007 International Mechanical Engineering Congress and Exposition, IMECE 2007, 11 November 2007 through 15 November 2007 ; Volume 2 , 2007 , Pages 263-270 ; 0791842967 (ISBN) Jahanyfard, E ; Firoozabadi, B ; Goodarzvand Chegini, A ; ASME ; Sharif University of Technology
    American Society of Mechanical Engineers (ASME)  2007
    One of the leading causes for death after heart diseases and cancer in all over the world is still stroke. Most strokes happen because an artery carrying blood from the heart to the brain is clogged. Most of the time, as with heart attacks, the problem is atherosclerosis, hardening of the arteries, calcified build up of fatty deposits on the vessel wall. The primary troublemaker is the carotid artery, one on each side of the neck, the main thoroughfare for blood to the brain. In this study, the fluid dynamic simulations were done in the carotid bifurcation artery for studying the formation of atherosclerosis, and shear thinning behavior of blood as well as Newtonian comportment was studied.... 

    Electrokinetically driven fluidic transport of power-law fluids in rectangular microchannels

    , Article Colloids and Surfaces A: Physicochemical and Engineering Aspects ; Volume 414 , 2012 , Pages 440-456 ; 09277757 (ISSN) Vakili, M. A ; Sadeghi, A ; Saidi, M. H ; Mozafari, A. A ; Sharif University of Technology
    Electroosmosis is the predominant mechanism for flow generation in lab-on-chip devices. Since most biofluids encountered in these devices are considered to be non-Newtonian, it is vital to study the flow characteristics of common non-Newtonian models under electroosmotic body force. In this paper, the hydrodynamically fully developed electroosmotic flow of power-law fluids in rectangular microchannels is analyzed. The electrical potential and momentum equations are numerically solved through a finite difference procedure for a non-uniform grid. A thoroughgoing parametric study reveals that the Poiseuille number is an increasing function of the channel aspect ratio, the zeta potential, the... 

    The effect of hematocrit and nanoparticles diameter on hemodynamic parameters and drug delivery in abdominal aortic aneurysm with consideration of blood pulsatile flow

    , Article Computer Methods and Programs in Biomedicine ; Volume 195 , October , 2020 Jafarzadeh, S ; Nasiri Sadr, A ; Kaffash, E ; Goudarzi, S ; Golab, E ; Karimipour, A ; Sharif University of Technology
    Elsevier Ireland Ltd  2020
    Background and Objective: The present article has simulated to investigate the efficient hemodynamic parameters, the drug persistence, and drug distribution on an abdominal aortic aneurysm. Methods: Blood as a non-Newtonian fluid enters the artery acting as a real pulse waveform; its behavior is dependent on hematocrit and strain rate. In this simulation of computational fluid dynamic, magnetic nanoparticles of iron oxide which were in advance coated with the drug, are injected into the artery during a cardiac cycle. A two-phase model was applied to investigate the distribution of these carriers. Results: The results are presented for different hematocrits and the nanoparticle diameter. It...