Sharif Digital Repository

Cell migration plays a key role in many biological processes including metastasis, wound healing, inflammatory response, body immune response and formation of new blood vessels. The migration of cells in response to the gradient of concentration gradient is regarded as chemotaxis. In the present study, the group chemotaxis of endothelial cells is simulated in response to gradient concentration of biochemical species using a developed cell migration model. At the first step, the numerical simulation of fluid flow and concentration transport of biochemical species is performed using a developed FVM code. At the second part, a model is developed to mimic the group migration of endothelial...