Search for: numerical-simulation-approaches
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    Analysis of Capillary-Viscous-Gravity Forces in Biopolymer Flooding with a Sensitivity Analysis on Polymer and Porous Medium Parameters

    , Article Journal of Dispersion Science and Technology ; Vol. 35, issue. 12 , Aug , 2014 , p. 1764-1773 Hamidpour, E ; Mirzaei-Paiaman, A ; Ramazani, S. A. A ; Hatami, A ; Sharif University of Technology
    Gravity, viscous, and capillary are three main forces affecting flow characteristics in porous media. No analytical solution can be found to model the flow by considering all these forces. In this work, by considering all these forces, the polymer-flooding process is modeled by using a numerical simulation approach. For characterizing the polymer, the modified Blake-Kozeny model is chosen, which benefits consideration of the permeability reduction due to polymer adsorption on the rock surface  

    Non-linear stress response of non-gap-spanning magnetic chains suspended in a newtonian fluid under oscillatory shear test: a direct numerical simulation

    , Article Physics of Fluids ; Volume 29, Issue 10 , 2017 ; 10706631 (ISSN) Hashemi, M. R ; Taghizadeh Manzari, M ; Fatehi, R ; Sharif University of Technology
    Adirect numerical simulation approach is used to investigate the effective non-linear viscoelastic stress response of non-gap-spanning magnetic chains suspended in a Newtonian fluid. The suspension is confined in a channel and the suspended clusters are formed under the influence of a constant external magnetic field. Large amplitude oscillatory shear (LAOS) tests are conducted to study the non-linear rheology of the system. The effect of inertia on the intensity of non-linearities is discussed for both magnetic and non-magnetic cases. By conducting magnetic sweep tests, the intensity and quality of the non-linear stress response are studied as a function of the strength of the external... 

    Design and simulation of an integrated centrifugal microfluidic device for CTCs separation and cell lysis

    , Article Micromachines ; Volume 11, Issue 7 , July , 2020 Nasiri, R ; Shamloo, A ; Akbari, J ; Tebon, P ; Dokmeci, M. R ; Ahadian, S ; Sharif University of Technology
    MDPI AG  2020
    Separation of circulating tumor cells (CTCs) from blood samples and subsequent DNA extraction from these cells play a crucial role in cancer research and drug discovery. Microfluidics is a versatile technology that has been applied to create niche solutions to biomedical applications, such as cell separation and mixing, droplet generation, bioprinting, and organs on a chip. Centrifugal microfluidic biochips created on compact disks show great potential in processing biological samples for point of care diagnostics. This study investigates the design and numerical simulation of an integrated microfluidic device, including a cell separation unit for isolating CTCs from a blood sample and a...