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    Simultaneous ammonium and nitrate removal by a modified intermittently aerated sequencing batch reactor (SBR) with multiple filling events

    , Article Polish Journal of Chemical Technology ; Volume 18, Issue 3 , 2016 , Pages 72-80 ; 15098117 (ISSN) Hajsardar, M ; Borghei, S. M ; Hassani, A. H ; Takdastan, A ; Sharif University of Technology
    De Gruyter Open Ltd 
    Abstract
    Optimized methods for simultaneous removal of nitrate, nitrite and ammonium are important features of nutrient removal. Nitrogen removal efficiency in an intermittently aerated sequencing batch reactor (IA-SBR) with multiple filling events was studied. No external carbon source was added and three filling events were considered. Oxidationreduction potential (ORP) and pH curve at solids retention time (SRT) of 20 d were analyzed. Effects of three organic loading rates (OLR), 0.67, 1.0 and 1.5 kgCOD/m3d, and three nitrogen loading rates (NLR), 0.054, 0.1 and 0.15 kgN/m3d, on nitrogen removal were studied. Nitrate Apex in pH curve and Nitrate Knee in ORP profile indicated that the end of... 

    The metabolic network model of primed/naive human embryonic stem cells underlines the importance of oxidation-reduction potential and tryptophan metabolism in primed pluripotency

    , Article Cell and Bioscience ; Volume 9, Issue 1 , 2019 ; 20453701 (ISSN) Yousefi, M ; Marashi, S. A ; Sharifi Zarchi, A ; Taleahmad, S ; Sharif University of Technology
    BioMed Central Ltd  2019
    Abstract
    Background: Pluripotency is proposed to exist in two different stages: Naive and Primed. Conventional human pluripotent cells are essentially in the primed stage. In recent years, several protocols have claimed to generate naive human embryonic stem cells (hESCs). To the best of our knowledge, none of these protocols is currently recognized as the gold standard method. Furthermore, the consistency of the resulting cells from these diverse protocols at the molecular level is yet to be shown. Additionally, little is known about the principles that govern the metabolic differences between naive and primed pluripotency. In this work, using a computational approach, we tried to shed light on... 

    A novel enzyme based biosensor for catechol detection in water samples using artificial neural network

    , Article Biochemical Engineering Journal ; Volume 128 , 2017 , Pages 1-11 ; 1369703X (ISSN) Maleki, N ; Kashanian, S ; Maleki, E ; Nazari, M ; Sharif University of Technology
    Elsevier B.V  2017
    Abstract
    Biosensors could be used as digital devices to measure the sample infield. Consequently, computational programming along with experimental achievements are required. In this study, a novel biosensor/artificial neural network (ANN) integrated system was developed. Poly (3,4-ethylenedioxy-thiophene)(PEDOT), graphene oxide nano-sheets (GONs) and laccase (Lac) were used to construct a biosensor. The simple and one-pot process was accomplished by electropolymerizing 3,4-ethylenedioxy-thiophene (EDOT) along with GONs and Lac as dopants on glassy carbon electrode. Scanning electron microscopy (SEM) and electrochemical characterization were conducted to confirm successful enzyme entrapment. The... 

    High yield of CO and synchronous s recovery from the conversion of CO2 and H2S in natural gas based on a novel electrochemical reactor

    , Article Environmental Science and Technology ; Volume 55, Issue 21 , 2021 , Pages 14854-14862 ; 0013936X (ISSN) Bai, J ; Zhang, B ; Zhang, Y ; Zhou, C ; Wang, P ; Zha, L ; Li, J ; Simchi, A ; Zhou, B ; Sharif University of Technology
    American Chemical Society  2021
    Abstract
    H2S and CO2 are the main impurities in raw natural gas, which needs to be purified before use. However, the comprehensive utilization of H2S and CO2 has been ignored. Herein, we proposed a fully resource-based method to convert toxic gas H2S and greenhouse gas CO2 synchronously into CO and elemental S by using a novel electrochemical reactor. The special designs include that, in the anodic chamber, H2S was oxidized rapidly to S based on the I−/I3− cyclic redox system to avoid anode passivation. On the other hand, in the cathodic chamber, CO2 was rapidly and selectively reduced to CO based on a porous carbon gas diffusion electrode (GDE) modified with polytetrafluoroethylene and cobalt... 

    Stimulus-responsive sequential release systems for drug and gene delivery

    , Article Nano Today ; Volume 34 , 2020 Ahmadi, S ; Rabiee, N ; Bagherzadeh, M ; Elmi, F ; Fatahi, Y ; Farjadian, F ; Baheiraei, N ; Nasseri, B ; Rabiee, M ; Tavakoli Dastjerd, N ; Valibeik, A ; Karimi, M ; Hamblin, M. R ; Sharif University of Technology
    Elsevier B.V  2020
    Abstract
    In recent years, a range of studies have been conducted with the aim to design and characterize delivery systems that are able to release multiple therapeutic agents in controlled and programmed temporal sequences, or with spatial resolution inside the body. This sequential release occurs in response to different stimuli, including changes in pH, redox potential, enzyme activity, temperature gradients, light irradiation, and by applying external magnetic and electrical fields. Sequential release (SR)-based delivery systems, are often based on a range of different micro- or nanocarriers and may offer a silver bullet in the battle against various diseases, such as cancer. Their distinctive...