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    Electrokinetic and aspect ratio effects on secondary flow of viscoelastic fluids in rectangular microchannels

    , Article Microfluidics and Nanofluidics ; Volume 20, Issue 8 , 2016 ; 16134982 (ISSN) Reshadi, M ; Saidi, M. H ; Firoozabadi, B ; Saidi, M. S ; Sharif University of Technology
    Springer Verlag  2016
    Abstract
    The secondary flow of PTT fluids in rectangular cross-sectional plane of microchannels under combined effects of electroosmotic and pressure driving forces is the subject of the present study. Employing second-order central finite difference method in a very refined grid network, we investigate the effect of electrokinetic and geometric parameters on the pattern, strength and the average of the secondary flow. In this regard, we try to illustrate the deformations of recirculating vortices due to change in the dimensionless Debye–Hückel and zeta potential parameters as well as channel aspect ratio. We demonstrate that, in the presence of thick electric double layers, significant alteration... 

    Synthetic biology-inspired robust-perfect-adaptation-achieving control systems: model reduction and stability analysis

    , Article IEEE Transactions on Control of Network Systems ; 2020 Mohammadie Zand, A ; Tavazoei, M. S ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2020
    Abstract
    In addition to perfectly steering the output concentration of a process network to an exogenous set-point, a desired synthetically implemented biological controller should be able to robustly maintain this regulated output in the face of the extrinsic disturbances and inherent uncertainties due to an evervarying environment besides the imprecise modeling. Such an ability, which is called robust perfect adaptation (RPA), can be achieved by integral feedback control (IFC). Answering how IFC is (biochemically) constructible in generally unknown synthetic networks has been a research focus in the community. One of these answers, which has been well investigated previously, is to utilize a simple...