Sharif Digital Repository

Numerous studies have shown a direct relationship between skeletal muscle active force and intracellular calcium ion concentrations; In fact, no matter how the muscle is stimulated (neurological, electrical, chemical, and mechanical stimuli), the main cause of muscle activation and consequently force generation is calcium ions.According to this scientific finding, the purpose of this study is to present a new chemo-mechanical multiscale model of skeletal muscle based on the fundamental principles of continuum thermodynamics. In this model, unlike other similar studies, muscle active force is not considered as the conventional multiplication of isometric force in a set of corrective...