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Performances evaluation of Photo-Fenton process and Sonolysis for the treatment of Penicillin G formulation effluent
, Article 1st 2011 International Conference on Environment Science and Biotechnology, ICESB 2011, Male, 25 November 2011 through 26 November 2011 ; Volume 8 , 2011 , Pages 202-208 ; 18780296 (ISSN) ; Emadian, S. M ; Vossoughi, M ; Sharif University of Technology
Abstract
Penicillin G is an active pharmaceutical ingredient of great importance in health sectors. Meanwhile, because of its huge quantity production and resistance to biodegradability, this antibiotic is ubiquitously presented in aquatic environment. In this study, the degradation of effluent wastewater from Penicillin G production plant by Photo- Fenton process and Ultrasound process (Sonolysis) was investigated, the effects of different process variables in both methods were evaluated and at last the degradation of Pen-G by these two processes in the optimum conditions was compared. Pen-G concentration and Chemical Oxygen Demand (COD) were selected as the environmental parameters to follow the...
Hybrid silk fibroin–gelatin nanofibrous sheet for drug delivery and regenerative medicine: In-vitro characterization and controlled release of simvastatin/protein
, Article Polymers for Advanced Technologies ; 2020 ; Alemzadeh, I ; Vossoughi, M ; Sharif University of Technology
John Wiley and Sons Ltd
2020
Abstract
Blend drug-loading method in electrospun scaffolds has gained much attention as a cost-effective and simple delivery system in regenerative medicine. However, it has some drawbacks, such as the burst release of encapsulated drugs and denaturing active agents in harsh organic solvents. In this study, a new silk fibroin-gelatin (SF–G) fibrous sheet has been introduced as an engineered scaffold and a straightforward drug delivery system for skin tissue engineering applications. The hybrid sheets have been prepared via co-electrospinning and in-situ crosslinking methods without corrosive solvents and toxic crosslinking agents. To evaluate the proposed scaffold as a controlled release system, the...
Hybrid silk fibroin–gelatin nanofibrous sheet for drug delivery and regenerative medicine: In-vitro characterization and controlled release of simvastatin/protein
, Article Polymers for Advanced Technologies ; Volume 32, Issue 3 , 2021 , Pages 1333-1344 ; 10427147 (ISSN) ; Alemzadeh, I ; Vossoughi, M ; Sharif University of Technology
John Wiley and Sons Ltd
2021
Abstract
Blend drug-loading method in electrospun scaffolds has gained much attention as a cost-effective and simple delivery system in regenerative medicine. However, it has some drawbacks, such as the burst release of encapsulated drugs and denaturing active agents in harsh organic solvents. In this study, a new silk fibroin-gelatin (SF–G) fibrous sheet has been introduced as an engineered scaffold and a straightforward drug delivery system for skin tissue engineering applications. The hybrid sheets have been prepared via co-electrospinning and in-situ crosslinking methods without corrosive solvents and toxic crosslinking agents. To evaluate the proposed scaffold as a controlled release system, the...