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Axial potential mapping of optical tweezers for biopolymer stretching: The bead size matters
, Article Optics Letters ; Volume 38, Issue 5 , 2013 , Pages 685-687 ; 01469592 (ISSN) ; Reihani, S. N. S ; Sharif University of Technology
2013
Abstract
Optical tweezers (OT) are widely used for pico (and femto)-Newton range force measurements. The appropriate choice of the bead size is not well understood for biopolymer stretching applications of OT. We have shown, both by theory and experiment, that wrong choice of the bead size could cause errors as large as 295% in the measured force. We provide a simple map for correct choice of the bead size and the direction of pulling for such applications. There is a good agreement between our theoretical and experimental results
Effect of intervertebral translational flexibilities on estimations of trunk muscle forces, kinematics, loads, and stability
, Article Computer Methods in Biomechanics and Biomedical Engineering ; Volume 18, Issue 16 , Sep , 2015 , Pages 1760-1767 ; 10255842 (ISSN) ; Arjmand, N ; Shirazi Adl, A ; Sharif University of Technology
Taylor and Francis Ltd
2015
Abstract
Due to the complexity of the human spinal motion segments, the intervertebral joints are often simulated in the musculoskeletal trunk models as pivots thus allowing no translational degrees of freedom (DOFs). This work aims to investigate, for the first time, the effect of such widely used assumption on trunk muscle forces, spinal loads, kinematics, and stability during a number of static activities. To address this, the shear deformable beam elements used in our nonlinear finite element (OFE) musculoskeletal model of the trunk were either substantially stiffened in translational directions (SFE model) or replaced by hinge joints interconnected through rotational springs (HFE model). Results...