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    Mathematical study of probe arrangement and nanoparticle injection effects on heat transfer during cryosurgery

    , Article Computers in Biology and Medicine ; Volume 66 , Nov , 2015 , Pages 113-119 ; 00104825 (ISSN) Mirkhalili, S. M ; Ramazani S. A. A ; Nazemidashtarjandi, S ; Sharif University of Technology
    Elsevier Ltd  2015
    Abstract
    Blood vessels, especially large vessels have a greater thermal effect on freezing tissue during cryosurgery. Vascular networks act as heat sources in tissue, and cause failure in cryosurgery and reappearance of cancer. The aim of this study is to numerically simulate the effect of probe location and multiprobe on heat transfer distribution. Furthermore, the effect of nanoparticles injection is studied. It is shown that the small probes location near large blood vessels could help to reduce the necessary time for tissue freezing. Nanoparticles injection shows that the thermal effect of blood vessel in tissue is improved. Using Au, Ag and diamond nanoparticles have the most growth of ice ball... 

    Evaluation of various energy windows at different radionuclides for scatter and attenuation correction in nuclear medicine

    , Article Annals of Nuclear Medicine ; Volume 29, Issue 4 , 2015 , Pages 375-383 ; 09147187 (ISSN) Asgari, A ; Ashoor, M ; Sohrabpour, M ; Shokrani, P ; Rezaei, A ; Sharif University of Technology
    Springer-Verlag Tokyo  2015
    Abstract
    Objective: Improving signal to noise ratio (SNR) and qualified images by the various methods is very important for detecting the abnormalities at the body organs. Scatter and attenuation of photons by the organs lead to errors in radiopharmaceutical estimation as well as degradation of images. The choice of suitable energy window and the radionuclide have a key role in nuclear medicine which appearing the lowest scatter fraction as well as having a nearly constant linear attenuation coefficient as a function of phantom thickness. Methods: The energy windows of symmetrical window (SW), asymmetric window (ASW), high window (WH) and low window (WL) using Tc-99m and Sm-153 radionuclide with... 

    High-throughput micro-solid phase extraction on 96-well plate using dodecyl methacrylate-ethylen glycol dimethacrylate monolithic copolymer

    , Article Analytica Chimica Acta ; Volume 792 , August , 2013 , Pages 59-65 ; 00032670 (ISSN) Bagheri, H ; Es'haghi, A ; Es-haghi, A ; Mohammadkhani, E ; Sharif University of Technology
    2013
    Abstract
    A novel high-throughput device based on 96-micro-solid phase extraction (96-μ-SPE) system was constructed for multiresidue determination of nine pesticides in aquatic samples. The extraction procedure was performed on a commercially available 96-well plate system. The extraction module consisted of 96 pieces of 1cm×3cm of cylindrically shaped stainless steel meshes. The prepared meshes were fixed in a home-made polytetrafluoroethylene-based constructed ninety-six holes block for possible simultaneous immersion of meshes into the center of individual wells. Dodecyl methacrylate and ethylene glycol dimethacrylate was copolymerized as a monolithic polymer and placed in the cylindrically shaped... 

    Grafting the sol-gel based sorbents by diazonium salts: A novel approach toward unbreakable capillary microextraction

    , Article Journal of Chromatography A ; Volume 1318 , November , 2013 , Pages 58-64 ; 00219673 (ISSN) Bagheri, H ; Bayat, P ; Piri Moghadam, H ; Sharif University of Technology
    2013
    Abstract
    The present work deals with a novel approach for grafting a sol-gel based sorbent, using diazonium salts for preparation of an unbreakable capillary microextraction (CME) device in on-line combination with high performance liquid chromatography (HPLC). The use of diazonium salts modifier allowed all types of metallic and non-metallic substrates to be used without any limitation. Substrates including copper, brass, stainless steel and polytetrafluoroethylene (PTFE) were chosen to be functionalized by chemical or electrochemical reduction of 4-amino phenyl acetic acid. Then, 3-(trimethoxysilyl)propylamine (3TMSPA) was selected as the precursor and the only reagent for preparation of the...