Loading...
Search for:
polyaniline-graphene
0.005 seconds
Design and fabrication of conductive nanofibrous scaffolds for neural tissue engineering: Process modeling via response surface methodology
, Article Journal of biomaterials applications ; Volume 33, Issue 5 , 2018 , Pages 619-629 ; 15308022 (ISSN) ; Mashayekhan, S ; Baniasadi, H ; Ramazani, A ; Ansarizadeh, M ; Sharif University of Technology
NLM (Medline)
2018
Abstract
Peripheral nervous system in contrary to central one has the potential for regeneration, but its regrowth requires proper environmental conditions and supporting growth factors. The aim of this study is to design and fabricate a conductive polyaniline/graphene nanoparticles incorporated gelatin nanofibrous scaffolds suitable for peripheral nervous system regeneration. The scaffolds were fabricated with electrospinning and the fabrication process was designed with Design-Expert software via response surface methodology. The effect of process parameters including applied voltage (kV), syringe pump flow rate (cm3/h), and PAG concentration (wt%), on the scaffold conductivity, nanofibers diameter,...
Conductive nanofiber scaffold for bone tissue engineering
, Article 24th Iranian Conference on Biomedical Engineering and 2017 2nd International Iranian Conference on Biomedical Engineering, ICBME 2017, 30 November 2017 through 1 December 2017 ; 2018 ; 9781538636091 (ISBN) ; Mashayekhan, S ; Abbaszadeh, H. A ; Ansarizadeh, M ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2018
Abstract
In order to fabricate nanofiber scaffold for bone tissue engineering, electrospinning technique was employed. This technique produces nanofiberous scaffold supporting cell adhesion, migration, and proliferation. Here, we developed a novel conductive scaffold from poly-caprolactone, gelatin, and poly aniline/graphene nanoparticles. In this study, co-electrospinning was utilized to fabricate composite electrospun scaffold. The effect of polyaniline/graphene (PAG) nanoparticles on the mechanical properties and electrical conductivity of this hybrid scaffold was investigated. The result showed that PAG nanoparticles enbance both mechanical properties and electrical conductivity of the scaffolds....
Bioinspired nanofiber scaffold for differentiating bone marrow-derived neural stem cells to oligodendrocyte-like cells: Design, fabrication, and characterization
, Article International Journal of Nanomedicine ; Volume 15 , 2020 , Pages 3903-3920 ; Mashayekhan, S ; Abbaszadeh, H. A ; Ansarizadeh, M ; Khoramgah, M. S ; Rahimi Movaghar, V ; Sharif University of Technology
Dove Medical Press Ltd
2020
Abstract
Background: Researchers are trying to study the mechanism of neural stem cells (NSCs) differentiation to oligodendrocyte-like cells (OLCs) as well as to enhance the selective differentiation of NSCs to oligodendrocytes. However, the limitation in nerve tissue acces-sibility to isolate the NSCs as well as their differentiation toward oligodendrocytes is still challenging. Purpose: In the present study, a hybrid polycaprolactone (PCL)-gelatin nanofiber scaffold mimicking the native extracellular matrix and axon morphology to direct the differentiation of bone marrow-derived NSCs to OLCs was introduced. Materials and Methods: In order to achieve a sustained release of T3, this factor was...