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    Synergy of titanium dioxide nanotubes and polyurethane properties for bypass graft application: Excellent flexibility and biocompatibility

    , Article Materials and Design ; Volume 215 , 2022 ; 02641275 (ISSN) Kianpour, G ; Bagheri, R ; Pourjavadi, A ; Ghanbari, H ; Sharif University of Technology
    Elsevier Ltd  2022
    Abstract
    A flexible, porous and biocompatible titanium dioxide nanotubes (TNT) - polyurethane (PU) film has been produced as a new scaffold for artificial vascular grafts. Synergistic improvements in the properties of vertical TNT and PU was reached, including enhancements in their biocompatibility, mechanical strength, flexibility and porosity. Open-ended (OE) TNT-PU and close-ended (CE) TNT-PU films were synthesized and their mechanical and biological properties were compared with their pure PU counterparts. TNT were attached to PU with a new strategy. The resulting flexible structure was hydrophilic and super hydrophilic in OE-TNT-PU and CE-TNT-PU scaffolds, respectively. The gas leakage during...