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Electrocardiographic ST-segment depression and exposure to traffic-related aerosols in elderly subjects with coronary artery disease
, Article Environmental Health Perspectives ; Volume 119, Issue 2 , Feb , 2011 , Pages 196-202 ; 00916765 (ISSN) ; Gillen, D. L ; Tjoa, T ; Staimer, N ; Polidori, A ; Arhami, M ; Sioutas, C ; Longhurst, J ; Sharif University of Technology
2011
Abstract
Background: Air pollutants have not been associated with ambulatory electrocardiographic evidence of ST-segment depression ≥ 1 mm (probable cardiac ischemia). We previously found that markers of primary (combustion-related) organic aerosols and gases were positively associated with circulating biomarkers of inflammation and ambulatory blood pressure in the present cohort panel study of elderly subjects with coronary artery disease. Objectives: We specifically aimed to evaluate whether exposure markers of primary organic aerosols and ultrafine particles were more strongly associated with ST-segment depression of ≥ 1 mm than were secondary organic aerosols or PM 2.5 (particulate matter with...