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psychogenic-nonepileptic-seizure
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Properties of functional brain networks correlate frequency of psychogenic non-epileptic seizures
, Article Frontiers in Human Neuroscience ; Issue DEC , 2012 ; 16625161 (ISSN) ; Joudaki, A ; Jalili, M ; Rossetti, A. O ; Frackowiak, R. S ; Knyazeva, M. G ; Sharif University of Technology
Frontiers Media S. A
2012
Abstract
Abnormalities in the topology of brain networks may be an important feature and etiological factor for psychogenic non-epileptic seizures (PNES). To explore this possibility, we applied a graph theoretical approach to functional networks based on resting state EEGs from 13 PNES patients and 13 age- and gender-matched controls. The networks were extracted from Laplacian-transformed time-series by a cross-correlation method. PNES patients showed close to normal local and global connectivity and small-world structure, estimated with clustering coefficient, modularity, global efficiency, and small-worldness metrics, respectively. Yet the number of PNES attacks per month correlated with a...