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    Modeling of Human Quadriceps Muscles and Design of a Magnetorheological Fluid-based Muscle Strengthening Device

    , M.Sc. Thesis Sharif University of Technology Seifi, Mohammad Mahdi (Author) ; Farahmand, Farzam (Supervisor) ; Behzadi Poor, Saeed (Supervisor)
    Abstract
    The Quadriceps Muscle as one of the major muscles of the human body plays a key role in knee function. Strengthening of this muscle is recommanded to prevent knee pain and even cure some diseases. Many believe that by strengthening the medial part with respect to the lateral part of the quadriceps muscles, patellofemoral pain syndrome can be prevented or treated. In this regard, a muscle strengthening system, based on magneticorheological brake is designed which provides isometric, isotonic and isokinetic exercise of knee joint and also enables the selective muscle strengthening. Beforehand a musculoskeletal model of lower extremity is developed in OpenSim software, capable to estimate force... 

    Prediction of Surgical Procedures Effect on Mal-tracking Correction of Patello-femoral Joint Using Patient-specific Musculo-skeletal Modeling

    , M.Sc. Thesis Sharif University of Technology Abedi, Rasoul (Author) ; Farahmand, Farzam (Supervisor) ; Zohoor, Hassan (Supervisor)
    Abstract
    According to the statistical studies, knee pain is the most common and costliest disorder after low back pain. One of its types is the patello-femoral disorder and instability. Patellar instability can be affected by different factors, such as: low depth of the trochlear groove, low height of the lateral femoral condyle, high length of the patellar tendon, abnormal lateral rotation of the tibia, unusual tibial attachment of the patellar tendon, small patellar size, general loosening of ligaments, etc. So, the mechanical properties of knee joint including patello-femoral joint, surrounding soft tissues, and incoming forces must be examined carefully, in order to find out suitable and... 

    Role of Thigh Muscle Changes in Knee Osteoarthritis Outcomes: Osteoarthritis Initiative Data

    , Article Radiology ; Volume 305, Issue 1 , 2022 , Pages 169-178 ; 00338419 (ISSN) Mohajer, B ; Dolatshahi, M ; Moradi, K ; Najafzadeh, N ; Eng, J ; Zikria, B ; Wan, M ; Cao, X ; Roemer, F. W ; Guermazi, A ; Demehri, S ; Sharif University of Technology
    Radiological Society of North America Inc  2022
    Abstract
    Background: Longitudinal data on the association of quantitative thigh muscle MRI markers with knee osteoarthritis (KOA) outcomes are scarce. These associations are of clinical importance, with potential use for thigh muscle–directed disease-modifying interventions. Purpose: To measure KOA-associated longitudinal changes in MRI-derived muscle cross-sectional area (CSA) and adipose tissue and their association with downstream symptom worsening and knee replacement (KR). Materials and Methods: In a secondary analysis of the Osteoarthritis Initiative multicenter prospective cohort (February 2004 through October 2015), knees of participants with available good-quality thigh MRI scans at baseline...