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quinone-derivative
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A one-pot, three-component regiospecific synthesis of dispiropyrrolidines containing a thiophenone ring via 1,3-dipolar cycloaddition reactions of azomethine ylides
, Article Tetrahedron Letters ; Volume 54, Issue 20 , May , 2013 , Pages 2520-2524 ; 00404039 (ISSN) ; Khodabakhshi, M. R ; Ghahremannejad, Z ; Foroushani, B. K ; Ng, S. W ; Sharif University of Technology
2013
Abstract
The synthesis of new dispiropyrrolidines containing a thiophenone ring has been achieved by a one-pot, three-component 1,3-dipolar cycloaddition reaction. Unsaturated thiophenone dipolarophiles were reacted with azomethine ylides, generated in situ from sarcosine and cycloketone derivatives (isatin, ninhydrin, acenaphthoquinone), to produce the corresponding cycloadducts in good yields (70-90%). The cycloaddition reaction was found to be highly regio- and diastereoselective
Solid state oxidation of phenols to quinones with ammonium persulfate/wet SiO2
, Article Journal of Chemical Research ; Issue 3 , 2005 , Pages 160-161 ; 03082342 (ISSN) ; Karimi Jaberi, Z ; Eftekhari Sis, B ; Sharif University of Technology
Scientific Reviews Ltd
2005
Abstract
A solid state method for the oxidation of phenols to quinones is described using ammonium persulfate/wet silica gel as oxidant
Mercaptotriazole as a nucleophile in addition to o-quinone electrochemically derived from catechol: Application to electrosynthesis of a new group of triazole compounds
, Article Electrochemistry Communications ; Volume 7, Issue 1 , 2005 , Pages 68-73 ; 13882481 (ISSN) ; Amiri, M ; Sharif University of Technology
2005
Abstract
Electrochemical oxidation of catechol in the presence of 3-mercapto-1,2,4-triazole (MTA) as a nucleophile in aqueous buffered solutions was studied by cyclic voltammetry and controlled-potential coulometry. The mechanism of electrochemical reaction is confirmed by spectrophotometric tracing in various times of controlled-potential coulometry. The voltammetric and spectrophotometric foundations indicate that a 1,4 Michael addition of MTA from its thiol moiety to the electrochemically derived o-quinone is occurred. The electrochemical synthesis of Michael addition product has been successfully accomplished by controlled-potential coulometry in a divided H-type cell and the reaction product was...
Anodic behavior of clioquinol at a glassy carbon electrode
, Article Bioelectrochemistry ; Volume 80, Issue 2 , 2011 , Pages 175-181 ; 15675394 (ISSN) ; Fernandes, I. P. G ; Oliveira, S. C. B ; Shahrokhian, S ; Oliveira-Brett, A. M ; Sharif University of Technology
2011
Abstract
Clioquinol is an antifungal, antiprotozoal and an Alzheimer's disease drug with cytotoxic activity toward human cancer cells. The electrochemical behavior of clioquinol and its oxidation product was studied using cyclic, differential pulse and square-wave voltammetry over a wide pH range on a glassy carbon electrode. The results revealed that the oxidation of clioquinol is an irreversible pH-dependent process that proceeds with the transfer of one electron and one proton in an adsorption-controlled mechanism and results in the formation of a main oxidation product, which adsorbs very strongly on the glassy carbon surface. The charge transfer coefficient was calculated as 0.64. The adsorbed...